Results 181 to 190 of about 92,133 (345)

Safety and Pharmacokinetics of Long‐Acting Monoclonal Antibodies Tixagevimab and Cilgavimab (AZD7442) in a China Phase 2 Study and Evaluation of Asian Race Effect

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Safety, pharmacokinetics, and impact of race of pharmacokinetics on monoclonal antibodies tixagevimab and cilgavimab (AZD7442) were assessed in Chinese adult participants in a Phase 2, randomized, double‐blind, placebo‐controlled trial. In total, 272 participants were randomized 3:1 to a single intravenous dose of 600 mg AZD7442 or placebo and
Jing Zhang   +10 more
wiley   +1 more source

Diagnóstico de leptospirosis humana: evaluación de la aglutinación macroscópica en diferentes etapas de la enfermedad

open access: yesSalud Pública de México, 2012
OBJETIVO: Evaluar la aglutinación macroscópica con antígeno termorresistente (TR) como tamiz diagnóstico de leptospirosis humana en diferentes etapas de la enfermedad.
Norma Bibiana Vanasco   +4 more
doaj  

Rubella infection after orthotopic liver transplantation [PDF]

open access: yes, 1994
Green, Michael   +5 more
core   +1 more source

A multipart phase 1 study of the safety, pharmacodynamics and pharmacokinetics of ALG‐055009, a novel thyroid hormone receptor beta (THR‐β) agonist for metabolic dysfunction‐associated steatohepatitis (MASH), in healthy participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi   +11 more
wiley   +1 more source

Serological tests for treponemal disease in adults in two Jamaican communities. [PDF]

open access: bronze, 1967
M. T. Ashcroft   +3 more
openalex   +1 more source

Clinical Pharmacogenetics Implementation Consortium Guideline for NAT2 Genotype and Hydralazine Therapy

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Hydralazine is a vasodilator typically used in the treatment of resistant hypertension and heart failure. N‐acetyltransferase 2 (NAT2) catalyzes the metabolism of hydralazine into inactive metabolites. NAT2 poor metabolizers (historically referred to as “slow acetylators”) are predicted to have increased plasma hydralazine concentrations compared with ...
Michael T. Eadon   +18 more
wiley   +1 more source

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