Results 31 to 40 of about 243,170 (161)
Classification Under Uncertainty: Data Analysis for Diagnostic Antibody Testing [PDF]
Formulating accurate and robust classification strategies is a key challenge of developing diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence and uncertainty therein can lead to significant classification errors. We present a novel method that leverages optimal decision theory to address this problem.
arxiv +1 more source
Sever hepatitis induced by Epstein-Barr virus: case series
Epstein-Barr virus (EBV) is a causative agent of infectious mononucleosis syndrome. This infection often resolves over a period of several months without outcomes, but may occasionally be complicated by a great variety of neurologic, hepatic, hematologic
Roushan Mohammad Reza Hasanjani+3 more
doaj +1 more source
Robust multiple method comparison and transformation [PDF]
A generalization of Passing-Bablok regression is proposed for comparing multiple measurement methods simultaneously. Possible applications include assay migration studies or interlaboratory trials. When comparing only two methods, the method reduces to the usual Passing-Bablok estimator. It is close in spirit to reduced major axis regression, which is,
arxiv
The ability of Pasteurella multocida to invade and multiply in its host is enhanced by the presence of the capsule, one of the most important virulence factors for this bacterium. Capsular typing methods are often used in epidemiological and pathogenesis
TQ Furian+6 more
doaj +1 more source
BackgroundThe global epidemiological situation of COVID-19 remains serious. The rapid hunting of SARS-CoV-2 infection is the key means for preventing transmission.MethodsA total of 40,689 consecutive overseas arrivals were screened for SARS-CoV-2 ...
Li-Li Fang+15 more
doaj +1 more source
Background and Objectives: SARS-CoV-2 is a newly discovered viral infection. It’s still unclear how antibodies react in infected individuals, and there is not enough evidence to support the clinical use of antibody examination.
Kiana Shirani+6 more
doaj +1 more source
Rapid Screening Evaluation of SARS-CoV-2 IgG Assays Using Z-Scores to Standardize Results
Many serologic tests are now available for measuring severe acute respiratory syndrome coronavirus 2 antibodies to evaluate potential protective immunity and for seroprevalence studies.
Marie K. Das+5 more
doaj +1 more source
A paper-based multiplexed serological test to monitor immunity against SARS-CoV-2 using machine learning [PDF]
The rapid spread of SARS-CoV-2 caused the COVID-19 pandemic and accelerated vaccine development to prevent the spread of the virus and control the disease. Given the sustained high infectivity and evolution of SARS-CoV-2, there is an ongoing interest in developing COVID-19 serology tests to monitor population-level immunity.
arxiv +1 more source
Prevalence Estimation and Optimal Classification Methods to Account for Time Dependence in Antibody Levels [PDF]
Serology testing can identify past infection by quantifying the immune response of an infected individual providing important public health guidance. Individual immune responses are time-dependent, which is reflected in antibody measurements. Moreover, the probability of obtaining a particular measurement changes due to prevalence as the disease ...
arxiv
Estimating force of infection from serologic surveys with imperfect tests.
BackgroundThe force of infection, or the rate at which susceptible individuals become infected, is an important public health measure for assessing the extent of outbreaks and the impact of control programs.Methods and findingsWe present Bayesian methods
Neal Alexander+2 more
doaj +1 more source