Results 31 to 40 of about 55,658 (304)

Rapid Screening Evaluation of SARS-CoV-2 IgG Assays Using Z-Scores to Standardize Results

open access: yesEmerging Infectious Diseases, 2020
Many serologic tests are now available for measuring severe acute respiratory syndrome coronavirus 2 antibodies to evaluate potential protective immunity and for seroprevalence studies.
Marie K. Das   +5 more
doaj   +1 more source

Guidelines for serological testing for syphilis [PDF]

open access: yesSexually Transmitted Infections, 2000
Although we may wish it were not so, syphilis, like the poor, will always be with us—at least for the foreseeable future. The levels of both are determined to a large extent, by political instability and socioeconomic deprivation. Overall, the incidence of syphilis is low in Western Europe (approximately 0.3 cases/100 000 in England in 1998)1 although ...
openaire   +4 more sources

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Practice Recommendations for Genetic Testing of Ataxias

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan   +7 more
wiley   +1 more source

PCR combined with serologic testing improves the yield and efficiency of SARS-CoV-2 infection hunting: A study in 40,689 consecutive overseas arrivals

open access: yesFrontiers in Public Health, 2023
BackgroundThe global epidemiological situation of COVID-19 remains serious. The rapid hunting of SARS-CoV-2 infection is the key means for preventing transmission.MethodsA total of 40,689 consecutive overseas arrivals were screened for SARS-CoV-2 ...
Li-Li Fang   +15 more
doaj   +1 more source

A Multi‐Center Retrospective Cohort Study of Neurosarcoidosis Myelitis: Current Observations and Future Directions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The optimal treatment for neurosarcoidosis myelitis is uncertain. We characterize incident neurosarcoidosis myelitis and assess treatment response by MRI and clinical scales. Methods Incident probable or definite neurosarcoidosis myelitis in adults was retrospectively identified from 13 academic medical centers.
Giovanna S. Manzano   +39 more
wiley   +1 more source

Evaluation of Commercially Available Serologic Diagnostic Tests for Chikungunya Virus

open access: yesEmerging Infectious Diseases, 2014
Chikungunya virus (CHIKV) is present or emerging in dengue virus–endemic areas. Infections caused by these viruses share some common signs/symptoms, but prognosis, patient care, and persistent symptoms differ.
Christine M. Prat   +5 more
doaj   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen   +18 more
wiley   +1 more source

Diagnostic value of antibody testing in comparison with lung scan and PCR in patients suspected of having COVID-19

open access: yesIranian Journal of Microbiology
Background and Objectives: SARS-CoV-2 is a newly discovered viral infection. It’s still unclear how antibodies react in infected individuals, and there is not enough evidence to support the clinical use of antibody examination.
Kiana Shirani   +6 more
doaj   +1 more source

Estimating force of infection from serologic surveys with imperfect tests.

open access: yesPLoS ONE, 2021
BackgroundThe force of infection, or the rate at which susceptible individuals become infected, is an important public health measure for assessing the extent of outbreaks and the impact of control programs.Methods and findingsWe present Bayesian methods
Neal Alexander   +2 more
doaj   +1 more source

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