Results 61 to 70 of about 55,658 (304)

Performance of serological tests PGL1 and NDO-LID in the diagnosis of leprosy in a reference Center in Brazil

BMC Infectious Diseases, 2019
Background Early detection of leprosy and multidrug therapy are crucial to achieve zero transmission and zero grade II incapacities goals of World Health Organization.
André Luiz Leturiondo, Ariani Batista Noronha, Monik Oney Oliveira do Nascimento, Cynthia de Oliveira Ferreira, Fabíola da Costa Rodrigues, Milton Ozório Moraes, Carolina Talhari   +6 more
doaj   +1 more source

Guidelines for serological testing for syphilis [PDF]

Sexually Transmitted Infections, 2001
Editor,—In our area the high HIV prevalence has made the interpretation of syphilis tests paticularly problematic. Coinfected …
openaire   +3 more sources

A Twist in the Diagnosis: Chronic Arthropathy Without Inflammation

Arthritis Care &Research, EarlyView.
María Á. Puche‐Larrubia, Inmaculada C. Aranda‐Valera, Alejandro Escudero‐Contreras, Rosa Roldán‐Molina   +3 more
wiley   +1 more source

CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target

Advanced Science, EarlyView.
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo, Xiaomeng Jia, Shenghong Wang, Xinyu Li, Yajing Liu, Lisen Lin, Zhengkun Wang, Fujun Liu, Slawomir Wolczynski, Nafis Rahman, Jie Gao, Xuguang Du, Suk‐Ying Tsang, Jiali Liu, Wei Song, Xiangdong Li   +15 more
wiley   +1 more source

Serological tests for syphilis. [PDF]

BMJ, 1982
N Monplaisir, J F Mornex
  +12 more sources

Constitutive Androstane Receptor in Macrophages Regulates Toll‐Like Receptor 4‐Mediated Innate Immune Responses Against Endotoxemic Liver Injury

Advanced Science, EarlyView.
The present study uncovers a novel role of constitutive androstane receptor (CAR) in inflammation‐mediated damage. CAR activation in macrophages inhibits proinflammatory macrophages by interacting with Tlr4, which protects against endotoxemic liver injury.
Renjie Cao, Tingting Zhao, Ying Wang, Shaofei Song, Yuan Li, Mengling Hou, Yanxin Zhang, Sengpeng Wong, Siqi Wang, Yuran Wang, Hong Peng, Min Huang, Yiming Jiang   +12 more
wiley   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

Effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in Londrina, Paraná State

Revista Brasileira de Hematologia e Hemoterapia, 2011
BACKGROUND: For transfusion purposes, blood donors must be accepted both in clinical and serological evaluations and must not have excluded their own donation using the confidential unit exclusion.
Ingridt Hildegard Vogler, Mariza Saito, Adriana Aparecida Spinosa, Marilza Celina da Silva, Egberto Munhoz, Edna Maria Vissoci Reiche   +5 more
doaj   +1 more source

In Vitro Monitoring of Babesia microti Infection Dynamics in Whole Blood Microenvironments

Advanced Science, EarlyView.
Here, an open microfluidic platform termed “µ‐Blood” is reported for real‐time, continuous monitoring of Babesia microti infection dynamics in vitro. µ‐Blood allows direct interrogation of whole blood with preserved integrity of the original whole blood microenvironment through an extended period (e.g., 72 h with mouse red blood cells) ex vivo. µ‐Blood
Chao Li, Emily G. Bache, Amy L. Apgar, Danielle M. Tufts, Tagbo H. R. Niepa   +4 more
wiley   +1 more source

Accuracy of capillary blood sampling for diagnosing syphilis infection

Scientific Reports
Capillary blood collection presents advantages such as reduced invasiveness over venous serum for syphilis diagnosing. This study aimed to compare diagnostic accuracy between capillary and venous blood samples for syphilis diagnosis.
Aniúsca Vieira dos Santos, Ana Carolina Monteiro da Rocha, Giovana Tavares dos Santos, Igor Araujo Vieira, Cáren Nunes de Oliveira, Suelen Basgalupp, Luana Giongo Pedrotti, Vinicius Serafini Roglio, Emerson Silveira de Brito, Thayane Martins Dornelles, Gerson Fernando Mendes Pereira, Flávia Moreno Alves de Souza, Eliana Marcia Wendland   +12 more
doaj   +1 more source