Granzyme K: A new frontier in systemic lupus erythematosus
The role of Granzyme K in the pathogenesis of systemic lupus erythematosus and its clinical translational significance. Abstract Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by dysregulated adaptive and innate immunity and aberrant complement activity.
Zhongyu Chen +5 more
wiley +1 more source
Human and Canine Seropositivity to <i>Toxocara canis</i> in Uralsk, Kazakhstan: Canine Egg Shedding and Evaluation of an Experimental ELISA. [PDF]
Davlyatshin T +10 more
europepmc +1 more source
Infection risk in rheumatoid arthritis patients treated with biologic and targeted therapies
In this context, infections associated with each biologic and targeted drug are summarized to inform the stratification of RA patients, including the characteristics of the susceptible patients and their concomitant therapy. We aim to provide a benefit‐risk analysis for clinical decision, and vital indications for the prevention of highly correlated ...
Lujing Wang, Jieshi Lin, Jie Qian
wiley +1 more source
An engineered anti-Oropouche virus human-murine chimeric immunoglobulin M is a viable substitute for positive human serum controls in diagnostic serology assays. [PDF]
Miazgowicz KL, Goodman CH, Calvert AE.
europepmc +1 more source
A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa +3 more
wiley +1 more source
Hepatitis B virus core immunoglobulin M: false positive more common than true. [PDF]
Landry ML, Bernard PE.
europepmc +1 more source
Porcine circovirus 2 vaccination timing was not associated with piglets’ serological response
Abstract Background The development of immunity in pigs starts in utero, but piglets are born immunologically immature and rely on maternal antibodies. Weaning exposes piglets to multiple stressors, yet vaccination is commonly performed around weaning.
Lea Uotinen +3 more
wiley +1 more source
Not Always 'Slapped Cheeks': Parvovirus B19 Infection Causing Severe Anaemia in a Kidney Transplant Recipient. [PDF]
Abdisalan A +4 more
europepmc +1 more source
Abstract Background Pet ferrets are typically vaccinated against distemper using a canine multivalent vaccine despite the lack of relevant safety or efficacy data. Here, we investigate the safety of a novel live canine parvovirus type 2c (CPV‐2c) vaccine strain and the efficacy of the live Onderstepoort canine distemper virus (CDV) vaccine strain used ...
Jacqueline Pearce +4 more
wiley +1 more source

