Results 71 to 80 of about 1,302,007 (304)

Association of Clonal Hematopoiesis With Incident, Late‐Onset, Seropositive Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Clonal hematopoiesis (CH), defined by acquired driver mutations in hematopoietic stem cells, is associated with many inflammatory diseases of aging. We investigated whether CH and its subtypes, CH of indeterminate potential (CHIP) and mosaic chromosomal alteration (mCA), are associated with incident rheumatoid arthritis (RA) and whether ...
Kun Zhao, Yash Pershad, J. Brett Heimlich, Michelle Ormseth, C. Michael Stein, Brian Sharber, Caitlyn Vlasschaert, Alexander G. Bick, Robert W. Corty   +8 more
wiley   +1 more source

Novel, cross-restricted, conserved, and immunodominant Cytotoxic T Lymphocyte epitopes in slow progressors in HIV Type 1 infection

, 1996
HIV-specific cytotoxic T lymphocytes (CTLs) play an important role in the immune response to HIV infection. Long-term nonprogressors (LTNPs) or slow progressors (SPs) in HIV infection may make qualitatively different CTL responses compared to those ...
KARL McINTYRE, RODNEY E. PHILLIPS, Phillips, Rodney, Krausa, P, Phillips, R.E., Giangrande, P, SIOBHAN CROWLEY, Edwards, A., McIntyre, K., MIKE BUNCE, Morgan, B., Edwards, A, McMichael, A.J., Crowley, S, BARBARA MORGAN, ANNE EDWARDS, Morgan, B, Bunce, M, McMichael, Andrew, PETER KRAUSA, Crowley, S., Krausa, P., Goulder, P.J.R., Goulder, PJ, McIntyre, K, PAUL GIANGRANDE, ANDREW J. McMICHAEL, Giangrande, P., PHILIP J.R. GOULDER, McMichael, AJ, Bunce, M., Phillips, RE   +31 more
core   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

Arthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki, Masaru Takeshita, Yuki Imai, Hiroyuki Fukui, Kazunori Furuhashi, Kotaro Matsumoto, Jun Kikuchi, Keiko Yoshimoto, Yuko Kaneko   +8 more
wiley   +1 more source

Diagnostic values of Helicobacter pylori diagnostic tests: stool antigen test, urea breath test, rapid urease test, serology and histology

, 2011
Background: The purpose of this study is to compare validity of 5 diagnostic tests of helicobacter pylori with each other: stool antigen test, urea breath test (UBT), rapid urease test (RUT), serology and histology.
Shadi Kazemi, Hamid Tavakkoli, Mohamad Reza Habizadeh, Mohammad Hasan Emami   +3 more
core  

Effects of automated alerts on unnecessarily repeated serology tests in a cardiovascular surgery department: a time series analysis

, 2010
Background Laboratory testing is frequently unnecessary, particularly repetitive testing. Among the interventions proposed to reduce unnecessary testing, Computerized Decision Support Systems (CDSS) have been shown to be effective, but their impact ...
Zapletal, Eric, Eric Zapletal, Pierre Durieux, Chevalier Patrick, Gillaizeau, Florence, Colombet, Isabelle, Patrick Chevalier, Chevalier, Patrick, Isabelle Colombet, Gillaizeau Florence, Niès Julie, Niès, Julie, Zapletal Eric, Julie Niès, Durieux Pierre, Durieux, Pierre, Colombet Isabelle, Florence Gillaizeau   +17 more
core   +1 more source

Image_2_Human bocavirus 1 is a genuine pathogen for acute respiratory tract infection in pediatric patients determined by nucleic acid, antigen, and serology tests.tif

, 2022
BackgroundHuman bocavirus 1 (HBoV1), first discovered in 2005, was positive in symptomatic and healthy children and co-detected with other respiratory viruses.
Dong-Mei Chen (1712968), Ri De (4437274), Yu-Tong Zhou (13172358), Ru-Nan Zhu (13172361), Yu Sun (18463), Yuan Qian (190308), Qi Guo (133147), Fang Wang (105926), Shuang Liu (8449), Ke-Xiang Zhang (13172355), Dong Qu (795826), Lin-Qing Zhao (13172364)   +11 more
core   +1 more source

Autoantibodies to Joint‐Related Peptides Are Associated With Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, EarlyView.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA) and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serologic markers. Methods We analyzed serum and plasma from three cohorts: presymptomatic individuals who later developed RA ...
Outi Sareila, Linda Johansson, Anders Lundquist, Monica Leu Agelii, Lei Cheng, Yibo He, Erik Lönnblom, Maria Andersson, Jan Kihlberg, Anders Esberg, Inger Gjertsson, Rikard Holmdahl, Solbritt Rantapää‐Dahlqvist   +12 more
wiley   +1 more source

Multiplex H. pylori serology and risk of gastric cardia and noncardia adenocarcinomas

, 2015
The reported associations with gastric adenocarcinoma and seropositivity to different Helicobacter pylori antigens using multiplex serology have not been consistent across studies.
Abnet, C. C., Murphy, G., Poustchi, H., Nasrollahzadeh, D., Dawsey, S. M., Sotoudeh, M., Shakeri, R., Malekzadeh, R., Michel, A., Islami, F., Brennan, P., Etemadi, A., Waterboer, T., Kamangar, F., Pawilta, M., Boffetta, P.   +15 more
core   +1 more source

Differences in SARS‐CoV‐2 Antigen Persistence in Individuals With Systemic Autoimmune Rheumatic Diseases Compared to the General Population: A RECOVER‐Adult Cohort Study

Arthritis &Rheumatology, EarlyView.
Objective Individuals with systemic autoimmune rheumatic diseases (SARDs) are at risk for worse acute and post–acute COVID‐19 outcomes, though whether individuals with SARDs have longer persistence of viral antigens after COVID‐19 has not been studied.
Naomi J. Patel, Zoe Swank, Jiaqi Wang, Xiaosong Wang, Lauren A. O'Keeffe, Madison Negron, Liya S. Getachew, Louise L. Hansen, Grace Qian, Alene A. Saavedra, Kevin T. Mueller, Natalie A. Davis, Kathleen M. M. Vanni, Sandria Savage, Julie S. Lam, Zachary S. Wallace, David R. Walt, Jeffrey A. Sparks, on behalf of RECOVER‐Adult   +18 more
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 CAR‐T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T‐cell therapy in patients with progressive systemic sclerosis. Methods Patients with progressive systemic sclerosis received CD19 CAR‐T cell therapy and were followed longitudinally for safety, clinical efficacy, immune ...
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source