Results 91 to 100 of about 89,599 (313)

Targeting Antigen‐Presenting Cells to Enhance the Tumor‐Spleen Immunity Cycle through Liposome‐Neoantigen Vaccine

open access: yesAdvanced Science, EarlyView.
LNPsD18, a cationic liposome that enhances antigen‐presenting cell uptake in the spleen and tumor without targeting ligands is developed. Co‐delivering neoantigens and a TLR9 agonist significantly improve DC activation, tumor immunity, and survival in liver and colorectal cancer models, demonstrating the importance of dual‐site APC targeting for cancer
Yu Xu   +12 more
wiley   +1 more source

PREDICT‐GTN 1: Can we improve the FIGO scoring system in gestational trophoblastic neoplasia?

open access: yesInternational Journal of Cancer, Volume 152, Issue 5, Page 986-997, 1 March 2023., 2023
What's new? The International Federation of Gynaecology and Obstetrics (FIGO) scoring system is used to predict resistance to first‐line single‐agent chemotherapy in gestational trophoblastic neoplasia (GTN) patients. HoweThis system is imperfect, however—one‐third of low‐risk patients develop resistance, and resistance rates increase with FIGO score ...
Victoria L. Parker   +14 more
wiley   +1 more source

Detection of Human Group a and C Rotaviruses in Pediatric Patients with Acute Gastroenteritis by Real TIME RT-PCR Assay: a Preliminary Study [PDF]

open access: yes, 2010
Rotavirus causes 25–55% of all hospital admissions for diarrhea and approximately 611.000 deaths every year in developing countries. Clinically, it is not possible to recognize the diarrhea caused by rotavirus and other infections.
Dewi, B. E. (Beti)   +3 more
core  

The epidemiology of canine leishmaniasis: transmission rates estimated from a cohort study in Amazonian Brazil [PDF]

open access: yes, 1997
We estimate the incidence rate, serological conversion rate and basic case reproduction number (R0) of Leishmania infantum from a cohort study of 126 domestic dogs exposed to natural infection rates over 2 years on Marajó Island, Pará State, Brazil.
Courtenay, O.   +3 more
core   +1 more source

Prognostic significance of six autoantibodies in esophageal squamous cell carcinoma: A prospective multi‐institutional study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The six autoantibodies (Sui1, p62, RalA, p53, NY‐ESO‐1 and c‐myc) positive group had poor prognosis compared to autoantibody negative group. A panel of autoantibodies against a tumor associated antigen in esophageal cancer patients had an additive effect with SCC‐Ag to detect esophageal SCC even in early stage.
Fumiaki Shiratori   +16 more
wiley   +1 more source

Statistical and Dynamical Study of Disease Propagation in a Small World Network [PDF]

open access: yes, 2001
We study numerically statistical properties and dynamical disease propagation using a percolation model on a one dimensional small world network. The parameters chosen correspond to a realistic network of school age children. We found that percolation threshold decreases as a power law as the short cut fluctuations increase. We found also the number of
arxiv   +1 more source

Cysticercosis and taeniasis cases diagnosed at two referral medical institutions, Belgium, 1990 to 2015 [PDF]

open access: yes, 2019
Background: Few case reports on human infections with the beef tapeworm Taenia saginata and the pork tapeworm, Taenia solium, diagnosed in Belgium have been published, yet the grey literature suggests a higher number of cases.
Bottieau, Emmanuel   +6 more
core   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

A paper-based multiplexed serological test to monitor immunity against SARS-CoV-2 using machine learning [PDF]

open access: yesACS Nano (2024)
The rapid spread of SARS-CoV-2 caused the COVID-19 pandemic and accelerated vaccine development to prevent the spread of the virus and control the disease. Given the sustained high infectivity and evolution of SARS-CoV-2, there is an ongoing interest in developing COVID-19 serology tests to monitor population-level immunity.
arxiv   +1 more source

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