Results 91 to 100 of about 267,153 (398)

Human cytomegalovirus (CMV) dysregulates neurodevelopmental pathways in cerebral organoids

Communications Biology
Human cytomegalovirus (CMV) infection is the leading non-genetic aetiology of congenital malformation in developed countries, causing significant fetal neurological injury.
Ece Egilmezer, Stuart T. Hamilton, Charles S. P. Foster, Manfred Marschall, William D. Rawlinson   +4 more
doaj   +1 more source

Differences in antibiotic and antiviral use in people with confirmed influenza: a retrospective comparison of rapid influenza PCR and multiplex respiratory virus PCR tests

BMC Infectious Diseases, 2021
Background Influenza is a highly contagious respiratory virus with clinical impacts on patient morbidity, mortality and hospital bed management. The effect of rapid nucleic acid testing (RPCR) in comparison to standard multiplex PCR (MPCR) diagnosis in ...
Victor Au Yeung, Kiran Thapa, William Rawlinson, Andrew Georgiou, Jeffrey J. Post, Kristen Overton   +5 more
doaj   +1 more source

The Serology of Bacillus polymyxa [PDF]

Journal of General Microbiology, 1951
SUMMARY: The spore, somatic and flagellar antigens of thirty-nine strains of Bacillus polymyxa have been investigated. The three antigens were serologically distinct and differed in thermal stability and in the appearance of the floccules after agglutination. The spore antigen was common to all the thirty-nine strains of B.
openaire   +4 more sources

Longitudinal Analysis of Antibody Responses to Trachoma Antigens Before and After Mass Drug Administration. [PDF]

, 2014
Blinding trachoma, caused by the bacteria Chlamydia trachomatis, is a neglected tropical disease targeted for elimination by 2020. A major component of the elimination strategy is mass drug administration (MDA) with azithromycin.
Dize, Laura, Gaydos, Charlotte, Goodhew, Erica Brook, Lammie, Patrick J, Martin, Diana L, Mkocha, Harran, Morgan, Sheri Maria, Munoz, Beatriz, Switzer, Andrew J, West, Sheila K, Wiegand, Ryan E   +10 more
core   +2 more sources

Accuracy of diagnostic codes and algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in administrative claims and electronic health records: systematic review and meta‐analysis.

Arthritis Care &Research, Accepted Article.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in electronic health records (EHRs). Methods We searched MEDLINE, Embase, and CENTRAL databases and included studies that validated case definitions against a reference standard such ...
Constanza Saka‐Herrán, Jessica Bennett, Yara Alkabti, Muhammad Fatir, Barbara Clyne, Caroline McCarthy, Gráinne Tynan, Nikki Dunne, Michelle Flood, Eoghan McCarthy, Frank Moriarty   +10 more
wiley   +1 more source

Geographic heterogeneity of SARS-CoV-2 circulation in Abidjan, Ivory Coast: a prospective study

Journal of Infection in Developing Countries
Introduction: Few studies on SARS-CoV-2 seroprevalence in Ivory Coast have been conducted since the first case was reported on March 11, 2020. The main objective of this study was to observe and better understand the circulation of SARS-CoV-2 in Abidjan.
Moussa Doumbia, Daouda Sevede, Viviane Kouakou, Pascal Pineau   +3 more
doaj   +1 more source

The impact of applying various de novo assembly and correction tools on the identification of genome characterization, drug resistance, and virulence factors of clinical isolates using ONT sequencing

BMC Biotechnology, 2023
Oxford Nanopore sequencing technology (ONT) is currently widely used due to its affordability, simplicity, and reliability. Despite the advantage ONT has over next-generation sequencing in detecting resistance genes in mobile genetic elements, its ...
Hussain A. Safar, Fatemah Alatar, Kother Nasser, Rehab Al-Ajmi, Wadha Alfouzan, Abu Salim Mustafa   +5 more
doaj   +1 more source

Identification of host–pathogen-disease relationships using a scalable multiplex serology platform in UK Biobank

Nature Communications, 2019
Certain infectious agents are recognised causes of cancer and other chronic diseases. To understand the pathological mechanisms underlying such relationships, here we design a Multiplex Serology platform to measure quantitative antibody responses against
A. Mentzer, N. Brenner, N. Allen, T. Littlejohns, A. Chong, A. Cortes, R. Almond, Michael R Hill, Simon Sheard, G. McVean, Allison Charles Ray Judy Tim Silvia Effrossyni Brian Paul Aiello Bangham Borrow Breuer Brooks Franceschi Gkr, A. Aiello, C. Bangham, R. Borrow, J. Breuer, T. Brooks, S. Franceschi, E. Gkrania-Klotsas, B. Greenwood, Paul D. Griffiths, E. Guy, K. Jeffery, D. Kelly, P. Klenerman, F. R. van der Klis, J. Knight, A. McMichael, V. Naranbhai, R. Pebody, T. Peto, A. Pollard, Thomas Schulz, K. Soldan, Graham W. Taylor, G. Towers, M. Tommasino, R. Weiss, D. Whitby, C. Wild, D. Wyllie, R. Collins, A. Hill, T. Waterboer   +42 more
semanticscholar   +1 more source

Acute febrile illness is associated with Rickettsia spp infection in dogs [PDF]

, 2015
BACKGROUND: Rickettsia conorii is transmitted by Rhipicephalus sanguineus ticks and causes Mediterranean Spotted Fever (MSF) in humans. Although dogs are considered the natural host of the vector, the clinical and epidemiological significance of R ...
A Cascio, A Estrada-Pena, A Mannelli, A Mura, A Ortuno, A Rojas, A Torina, A Torina, A Torina, A Znazen, Alessandra Caprì, AM Gasser, BA Stillman, C Colomba, C Riera, C Rovery, CP Ober, D Otranto, D Otranto, D Otranto, E Beeler, E Sanger, EB Breitschwerdt, F Segura-Porta, FJ Marquez, G Baneth, G Baneth, G Baneth, G Vitale, GB Andrade, GM Giammanco, GM Giammanco, H Inokuma, J Fuente de la, JC Garcia-Garcia, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, Laia Solano-Gallego, M Bernabeu-Wittel, M Rene-Martellet, M Sarih, Marco Caldin, Maria Grazia Pennisi, ME Eremeeva, ME Mylonakis, Michele Trotta, ML Levin, ML Levin, N Alexandre, N Cardenosa, NY Salem, P Brouqui, P Brouqui, P Parola, P Parola, PJ Kelly, S Delgado, S Harrus, S Harrus, S Santibanez, SE Little, T Beninati, T Furlanello, Tommaso Furlanello, WL Nicholson   +69 more
core   +2 more sources

Engineering Highly Cellularized Living Materials via Mechanical Agitation

Advanced Functional Materials, EarlyView.
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani, Shiyu Liu, Evan Johnston, Weiyi Wan, Xiaoyi Lan, Tianqin Ning, Alexander Nottegar, Ran Huo, Shuaibing Jiang, Jianyu Li   +9 more
wiley   +1 more source