Results 131 to 140 of about 89,599 (313)

Treatment outcomes and costs of a simplified antiretroviral treatment strategy for hepatitis C among Hepatitis C Virus and Human Immuno deficiency Virus co‐infected patients in Ukraine

JGH Open, Volume 6, Issue 12, Page 894-903, December 2022., 2022
We assessed treatment and cost outcomes for integrated HIV and viral hepatitis testing with ledipasvir/sofosbuvir ± weight‐based ribavirin for 12 weeks in Kyiv, Ukraine. Overall, a sustained virological response (SVR) was achieved in 831 of 868 patients (95.7%).
Sergie Antoniak, Charles S Chasela, Morgan Julie Freiman, Yulia Stopolianska, Tetiana Barnard, Malini M Gandhi, Maria Liulchuk, Zhanna Tsenilova, Tretiakov Viktor, Jeri Dible, Constance Wose Kinge, Francis Akpan, Thomas Minior, Ntombi Sigwebela, Sofiane Mohamed, Matthiue Barralon, Fadzai Marange, Clint Cavenaugh, Charles Vander Horst, Svitlana Antonyak, Thembisile Xulu, Kara W Chew, Ian Sanne, Sydney Rosen, for EQUIP Health   +24 more
wiley   +1 more source

PepSIRF: a flexible and comprehensive tool for the analysis of data from highly-multiplexed DNA-barcoded peptide assays [PDF]

arXiv, 2020
By coupling peptides with DNA tags (i.e., 'barcodes'), it is now possible to harness high-throughput sequencing (HTS) technologies to enable highly multiplexed peptide-based assays, which have a variety of potential applications including broad characterization of the epitopes recognized by antibodies.
arxiv  

Diversity and Dynamics of Indigenous \u3cem\u3eRhizobium japonicum\u3c/em\u3e Populations [PDF]

, 1980
A simple method, based upon the separation of cellular proteins by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis, has been devised for distinguishing between isolates of Rhizobium japonicum.
Brill, Winston J., Noel, K. Dale
core   +1 more source

Endogenous Retroelement Activation is Implicated in Interferon‐α Production and Anti–Cyclic Citrullinated Peptide Autoantibody Generation in Early Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Endogenous retroelements (EREs) stimulate type 1 interferon (IFN‐I) production but have not been explored as potential interferonogenic triggers in rheumatoid arthritis (RA). We investigated ERE expression in early RA (eRA), a period in which IFN‐I levels are increased.
Faye A. H. Cooles, Gemma Vidal Pedrola, Najib Naamane, Arthur G. Pratt, Ben Barron‐Millar, Amy E. Anderson, Catharien M. U. Hilkens, John Casement, Vincent Bondet, Darragh Duffy, Fan Zhang, Ruchi Shukla, John D. Isaacs   +12 more
wiley   +1 more source

Obliterative portal venopathy: A neglected and probably misdiagnosed disease with peculiar etiology in South America

JGH Open, Volume 6, Issue 12, Page 904-909, December 2022., 2022
Classically described in the group of non‐cirrhotic portal hypertension, obliterative portal venopathy (OPV) causes are still unknown. Our aim is to describe the characteristics of 43 OPV patients and potential risk factors. Clinically significant portal hypertension was found in 28% of cases. The most frequent indication for liver biopsy was elevation
Vinícius Nunes, Luiz A R de Freitas, Juliana R de Freitas, Caio Araújo, Gildásio N Junior, Maria I Schinoni, Fernando Bessone, Raymundo Paraná   +7 more
wiley   +1 more source

Holographic immunoassays [PDF]

arXiv, 2020
The size of a probe bead reported by holographic particle characterization depends on the proportion of the surface area covered by bound target molecules and so can be used as an assay for molecular binding. We validate this technique by measuring the kinetics of irreversible binding for the antibodies immunoglobulin G (IgG) and immunoglobulin M (IgM)
arxiv  

An Immunosenescent CD8+ T Cell Subset in Patients with Axial Spondyloarthritis and Psoriatic Arthritis Links Spontaneous Motility to Telomere Shortening and Dysfunction

Arthritis &Rheumatology, EarlyView.
Objective A pathogenetic role of CD8+ T lymphocytes in radiographic axial spondyloarthritis (r‐axSpA) and other spondyloarthritis (SpA) is sustained by genome‐wide association studies and by the expansion of public T cell clonotypes in the target tissues.
Giorgia Paldino, Valentina Tedeschi, Valentina Proganò, Erica Salvati, Valerio Licursi, Eleonora Vertecchi, Alexandru L. Bivolaru, Emanuele Molteni, Rossana Scrivo, Mattia Congia, Alberto Cauli, Rosalba Caccavale, Marino Paroli, Martina Kunkl, Loretta Tuosto, Rosa Sorrentino, Maria Teresa Fiorillo   +16 more
wiley   +1 more source

Management of Helicobacter pylori infection

JGH Open, Volume 7, Issue 1, Page 3-15, January 2023., 2023
Antibiotic‐resistant H. pylori strains have been increasing in most regions. Recommended first‐line regimens for H. pylori eradication are classified according to clarithromycin resistance. For patients with multiple treatment failure, antimicrobial susceptibility testing (AST) should be performed. Abstract Helicobacter pylori infection exhibits a wide
Natsuda Aumpan, Varocha Mahachai, Ratha‐korn Vilaichone   +2 more
wiley   +1 more source

Failure in syndromic management due to drug-resistant Mycoplasma genitalium in Florianópolis, South Brazil

DST
Introduction: Mycoplasma genitalium is a bacterium associated with sexually transmitted infections that can cause urethritis in men and complications in women, including preterm birth. Increasing macrolide resistance in M. genitalium poses challenges to
Fernando Hartmann Barazzetti, Marcos André Schörner, Jhonatan Augusto Ribeiro, Henrique Borges da Silva Grisard, Jéssica Motta Martins, Julia Kinetz Wachter, Patrícia de Almeida Vanny, Maria Luiza Bazzo   +7 more
doaj   +1 more source

Genome Sequence Classification for Animal Diagnostics with Graph Representations and Deep Neural Networks [PDF]

arXiv, 2020
Bovine Respiratory Disease Complex (BRDC) is a complex respiratory disease in cattle with multiple etiologies, including bacterial and viral. It is estimated that mortality, morbidity, therapy, and quarantine resulting from BRDC account for significant losses in the cattle industry.
arxiv