Results 131 to 140 of about 274,252 (355)

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Francisella tularensis Transmission by Solid Organ Transplantation, 20171. [PDF]

, 2019
In July 2017, fever and sepsis developed in 3 recipients of solid organs (1 heart and 2 kidneys) from a common donor in the United States; 1 of the kidney recipients died.
Annambhotla, Pallavi, Asad, Shadaba, Aslam, Saima, Basavaraju, Sridhar V, Brown, Jennifer, Burns, Kevin, Carifo, Karen, Dagher, Hikmat N, Fritz, Curtis L, Gonzalez, Anthony, Ham, John, Helsel, Elizabeth, Hinckley, Alison F, Iser, Joseph, Johnson, Michael, Jones, Jefferson M, Kelley, Walter E, Kingry, Luke C, Krafft, Melissa, Kwit, Natalie A, Medina-Garcia, Luis H, Mohler, Kelli, Murua, Christian, Nelson, Christina A, Petersen, Jeannine M, Respicio-Kingry, Laurel, Tularemia in Transplant Recipients Investigation Team, Wiggins, Landon, Zhang, Ying   +28 more
core  

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Modifying of fibronectin accumulation pharmacologically diminishes bone metastasis growth by suppressing proliferation

Bone Reports, 2021
Hiba Ghura, Stefan Hamelmann, Inaam Nakchbandi   +2 more
doaj   +1 more source

Somatic mosaicisms of chromosome 1 at two different stages of ontogenetic development detected by Rh blood group discrepancies

Haematologica, 2019
Spontaneous Rh blood group changes are a striking sign, reported to occur mainly in patients with hematologic disorders. Upon routine blood grouping, 2 unrelated individuals showed unexplained mixed red cell phenotype regarding the highly immunogenic c ...
Eva-Maria Dauber, Wolfgang R. Mayr, Hein Hustinx, Marlies Schönbacher, Holger Budde, Tobias J. Legler, Margit König, Oskar A. Haas, Gerhard Fritsch, Günther F. Körmöczi   +9 more
doaj   +1 more source

Serology of paracoccidioidomycosis [PDF]

Mycopathologia, 2008
This review provides the background for understanding the role of a battery of diagnostic methods in paracoccidioidomycosis (PCM). This systemic mycosis is a disease endemic in many regions of Latin America, with sporadic cases also occurring throughout the world (mycosis of importation).
openaire   +2 more sources

Estimating cholera incidence with cross-sectional serology

Science Translational Medicine, 2019
Cross-sectional Vibrio cholerae–related antibody measures can be used to estimate cholera incidence in a population. Estimating the true prevalence of cholera Successful development of anti-cholera measures requires accurate estimates of infection ...
A. Azman, J. Lessler, F. Luquero, Tafiqur R. Bhuiyan, A. Khan, F. Chowdhury, Alamgir Kabir, M. Gurwith, Ana A. Weil, J. Harris, S. Calderwood, E. Ryan, F. Qadri, D. Leung   +13 more
semanticscholar   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Vaccine sero-monitoring and sero-surveillance of Peste des petits ruminants in small ruminants in West Gojjam zone, Amhara region, Ethiopia

Frontiers in Veterinary Science
BackgroundPeste des petits ruminants (PPR) is an acute or subacute, highly contagious, and economically important, transboundary disease of small ruminants caused by Peste des petits ruminants virus (PPRV).ObjectivesThe objective of this study was to ...
Mesafint Mandefro, Saddam Mohammed Ibrahim, Demeke Sibhatu, Nebiyou Kassa, Kemal Emiyu, Kebede Debebe, Bereket Dessalegn, Mastewal Birhan, Molalegne Bitew   +8 more
doaj   +1 more source

Chromatographic separation of plasmalogenic, alkyl-acyl, and diacyl forms of ethanolamine glycerophosphatides

Journal of Lipid Research, 1968
The plasmalogenic, alkyl-acyl, and diacyl forms of ethanolamine glycerophosphatides were completely separated from each other as methylated dinitrophenyl derivatives by thin-layer chromatography on Silica Gel G. The relatively high resolving power needed
Ossi Renkonen
doaj   +1 more source