Results 221 to 230 of about 209,522 (357)

Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife

Biological Reviews, EarlyView.
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief, Sandra Bouwhuis, Anja Globig, Anne Günther, Wouter Courtens   +4 more
wiley   +1 more source

Fatal European subtype tick-borne encephalitis in a fully vaccinated immunocompetent child: a case report with viral sequencing. [PDF]

BMC Infect Dis
Sondén K, Lindsjö OK, Vonlanthen S, Gisslén M, Kinch A.   +4 more
europepmc   +1 more source

Surgical management of persistent gingival recession after sepsis‐associated gingival necrosis in a patient with systemic lupus erythematosus: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Sepsis‐associated gingival necrosis is an uncommon oral manifestation that may result in extensive gingival recession after the resolution of the acute phase. Methods This report presents the 2‐year follow‐up of periodontal management in a 38‐year‐old woman with systemic lupus erythematosus, who developed septic shock accompanied by
Risako Mikami, Koji Mizutani, Ruriko Mizuno, Yuji Kabasawa, Koichiro Matsuo   +4 more
wiley   +1 more source

Optimising COVID-19 episode identification using serology and PCR/rapid antigen testing: insights from the BRACE trial. [PDF]

BMC Infect Dis
McDonald E, Pittet LF, Bonten M, Byrne A, Campbell J, Croda J, Dalcolmo M, Davidson AJ, Dos Santos G, Gardiner K, Gwee A, Jardim B, Lacerda M, Lucas M, Lynn DJ, Manning L, Marshall H, Perrett KP, Prat-Aymerich C, Puga MAM, Richmond P, Rodríguez-Baño J, Wadia U, Warris A, Wood N, Curtis N, Messina NL, BRACE Trial Consortium Group.   +27 more
europepmc   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Cardiovascular Manifestations Documented in Patients with Lyme Disease: Clinical Presentation, Management Strategies, and Outcomes. [PDF]

Infect Dis Rep
Cortes Islas LA, Bartolo Gomez PM, Cuevas Obispo ND, Xicohtencatl Muñoz A, Lucero LYL, Ramirez Hinojosa JP.   +5 more
europepmc   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

Agreement Between Self-Reported COVID-19 and Dried Blood Spot Serology: A Cross-Sectional Study. [PDF]

Health Sci Rep
Sheppard N, Carroll MTC, Borg BM, Toh ZQ, Licciardi PV, Smith CL, Ikin JF, Abramson MJ, Walker-Bone K, Lane TJ.   +9 more
europepmc   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source

Illustrative case series of eosinophilia in UK Armed Forces personnel and recommended management for non-specialists. [PDF]

BMJ Mil Health
Kain MJW, Hughes C, Nevin W, Defres S, Checkley A, Bailey M, O'Shea MK, Fletcher T, Beeching NJ, Woolley S.   +9 more
europepmc   +1 more source