Results 41 to 50 of about 183,686 (358)

Commercial Serology Assays Predict Neutralization Activity Against SARS-CoV-2

medRxiv, 2020
Background. Currently it is unknown whether a positive serology results correlates with protective immunity against SARS-CoV-2. There are also concerns regarding the low positive predictive value of SARS-CoV-2 serology tests, especially when testing ...
R. Suhandynata, M. Hoffman, Deli Huang, J. T. Tran, M. Kelner, S. Reed, R. McLawhon, J. Voss, D. Nemazee, R. Fitzgerald   +9 more
semanticscholar   +1 more source

Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays

bioRxiv, 2020
The SARS-CoV-2 spike trimer is the primary antigen for several serology assays critical to determining the extent of SARS-CoV-2 exposure in the population.
D. Esposito, Jennifer L. Mehalko, Matthew R Drew, Kelly R. Snead, Vanessa E. Wall, Troy Taylor, Peter H. Frank, J. Denson, Min Hong, G. Gulten, Kaitlyn Sadtler, S. Messing, W. Gillette   +12 more
semanticscholar   +1 more source

AGA Clinical Practice Update on Diagnosis and Monitoring of Celiac Disease-Changing Utility of Serology and Histologic Measures: Expert Review.

Gastroenterology, 2019
PURPOSE The purpose of this clinical practice update is to define key modalities in the diagnosis and monitoring of celiac disease (CD) in adults as well as in children and adolescents.
S. Husby, J. Murray, D. Katzka
semanticscholar   +1 more source

Comprehensive, comparative evaluation of 25 automated SARS-CoV-2 serology assays

Microbiology Spectrum
The onset of the COVID-19 pandemic resulted in hundreds of in vitro devices coming to market, facilitated by regulatory authorities allowing “Emergency Use,” without a prior comprehensive evaluation of performance.
Wayne Dimech, Shannon Curley, Jing Jing Cai   +2 more
doaj   +1 more source

Retrospective Study Investigating the Prevalence and Clinical Significance of Hepatitis B Virus Precore and Basal Core Promoter Variants

Canadian Journal of Gastroenterology and Hepatology, 2015
BACKGROUND: Hepatitis B virus (HBV) precore (PC) and basal core promoter (BCP) variants are well known; however, their prevalence in North America is unclear, especially among hepatitis B e antigen-negative patients.
Meaghan O’Brien, Adara Casselman, Gerry Smart, Ainsley Gretchen, Kelly Kaita, Kamran Kadkhoda   +5 more
doaj   +1 more source

Significance of serology testing to assist timely diagnosis of SARS-CoV-2 infections: implication from a family cluster

Emerging Microbes and Infections, 2020
Confirmative diagnosis of SARS-CoV-2 infections has been challenged due to unsatisfactory positive rate of molecular assays. Here we identified a family cluster of SARS-CoV-2 infections, with five of six family members were SARS-CoV-2-specific ...
Yan Xu, M. Xiao, Xinchao Liu, Sheng-yong Xu, Tie-kuan Du, Jun Xu, Qiwen Yang, Yingchun Xu, Yang Han, Taisheng Li, Huadong Zhu, Mengzhao Wang   +11 more
semanticscholar   +1 more source

Epidemiological Study of the Antimicrobial Resistance Pattern of a Suspected Urinary Tract Infection in a Super Surgical, Super Specialty Hospital in Northern India

Medical Sciences Forum, 2023
Background: This study aimed to assess the antimicrobial resistance profiles of urinary tract infection (UTI) collected from individuals of various age groups, both male and female. Methods: This study analyzed 266 urine samples from diverse individuals.
Narayan Ahirwar, Tapan Kumar Singha, Malvika Srivastava, Manisha Pal   +3 more
doaj   +1 more source

Meta-analysis of diagnostic performance of serology tests for COVID-19: impact of assay design and post-symptom-onset intervals

Emerging Microbes and Infections, 2020
Serology detection is recognized for its sensitivity in convalescent patients with COVID-19, in comparison with nucleic acid amplification tests (NAATs).
Hongyu Wang, Jingwen Ai, M. Loeffelholz, Yi-Wei Tang, Wenhong Zhang   +4 more
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source