Results 31 to 40 of about 66,706 (287)

Serotonergic innervation of the amygdala is increased in autism spectrum disorder and decreased in Williams syndrome

Molecular Autism, 2020
Background Williams syndrome (WS) and autism spectrum disorder (ASD) are neurodevelopmental disorders that demonstrate overlapping genetic associations, dichotomous sociobehavioral phenotypes, and dichotomous pathological differences in neuronal ...
C. H. Lew, K. M. Groeniger, K. L. Hanson, D. Cuevas, D. M. Z. Greiner, B. Hrvoj-Mihic, U. Bellugi, C. M. Schumann, K. Semendeferi   +8 more
doaj   +1 more source

Cartography of Serotonergic Circuits [PDF]

Neuron, 2014
Serotonin is an essential neuromodulator, but the precise circuit connectivity that regulates serotonergic neurons has not been well defined. Using rabies virus tracing strategies Weissbourd et al. (2014) and Pollak Dorocic et al. (2014) in this issue of Neuron and Ogawa et al.
Sparta, Dennis R., Stuber, Garret D.
openaire   +2 more sources

Topographical Organization of M-Current on Dorsal and Median Raphe Serotonergic Neurons

Frontiers in Cellular Neuroscience, 2021
Dorsal and median raphe nuclei (DR and MR, respectively) are members of the reticular activating system and play important role in the regulation of the sleep-wakefulness cycle, movement, and affective states.
Tsogbadrakh Bayasgalan, Andrea Csemer, Adrienn Kovacs, Krisztina Pocsai, Balazs Pal   +4 more
doaj   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Antidepressant-like Effects of Garcinia nigrolineata Resin Extract in a Chronic Mild Stress Mouse Model: Modulation of Monoaminergic and HPA-Axis Pathways

Plants
The resin extract of Garcinia nigrolineata (GNR-E), a tropical plant used in Southeast Asian traditional medicine, was evaluated for its antidepressant-like effects in a chronic mild stress (CMS) mouse model, with imipramine as a reference drug.
Yutthana Chotritthirong, Yaowared Sumanont, Supawadee Daodee, Abdulwaris Mading, Chantana Boonyarat, Charinya Khamphukdee, Decha Kumla, Juthamart Maneenet, Kinzo Matsumoto, Anake Kijjoa, Suresh Awale, Orawan Monthakantirat   +11 more
doaj   +1 more source

Cannabinoid type-1 receptor signaling in central serotonergic neurons regulates anxiety-like behavior and sociability

Frontiers in Behavioral Neuroscience, 2015
The endocannabinoid system possesses neuromodulatory functions by influencing the release of various neurotransmitters, including γ-aminobutyric acid (GABA) and glutamate.
Beat eLutz, Martin eHäring, Vanessa eEnk, Alejandro eAparisi Rey, Sebastian eLoch, Inigo eRuiz De Azua, Krisztina eMonory, Tillmann eWeber, Dusan eBartsch   +8 more
doaj   +1 more source

Endocannabinergic modulation of central serotonergic activity in healthy human volunteers

Annals of General Psychiatry, 2023
Background The serotonergic and the endocannabinoid system are involved in the etiology of depression. Depressive patients exhibit low serotonergic activity and decreased level of the endocannabinoids anandamide (AEA) and 2-arachidonylglycerol (2AG ...
Barbara Emons, Larissa Arning, Vera-Estelle Makulla, Maria-Theresia Suchy, Dimitrios Tsikas, Thomas Lücke, Jörg T. Epplen, Georg Juckel, Patrik Roser   +8 more
doaj   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Dissecting the serotonergic food signal stimulating sensory-mediated aversive behavior in C. elegans. [PDF]

PLoS ONE, 2011
Nutritional state often modulates olfaction and in Caenorhabditis elegans food stimulates aversive responses mediated by the nociceptive ASH sensory neurons.
Gareth Harris, Amanda Korchnak, Philip Summers, Vera Hapiak, Wen Jing Law, Andrew M Stein, Patricia Komuniecki, Richard Komuniecki   +7 more
doaj   +1 more source

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

Arthritis Care &Research, Accepted Article.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high magnitude stress.
Jay B. Higgs, Willie J. Hale, Casey L. Straud, Jim Mintz, Stacey Young‐McCaughan, Kimberly D. Gomes, Chelsea J. Sterne, Katrina M. Lawrence‐Wolff, Alan J. Bartholomew, Kevin M. Kelly, Douglas M. Maurer, Catherine Vriend, Brett T. Litz, Douglas E. Williamson, Alan L. Peterson, for the STRONG STAR Consortium   +15 more
wiley   +1 more source