Serotonin and noradrenaline reuptake inhibitors improve micturition control in mice. [PDF]
Poor micturition control may cause profound distress, because proper voiding is mandatory for an active social life. Micturition results from the subtle interplay of central and peripheral components.
Marco Redaelli+6 more
doaj +7 more sources
Serotonin Reuptake Inhibitor Increases Pseudarthrosis Rates in Anterior Cervical Discectomy and Fusions [PDF]
Study Design Retrospective cohort. Purpose To determine (1) the effects of serotonin reuptake inhibitors in pseudarthrosis rates after anterior cervical decompression and fusion (ACDF) and (2) to identify patient-reported outcome measures in patients ...
Mark James Lambrechts+15 more
doaj +2 more sources
Abnormal Thyroid Function Laboratory Results Caused by Selective Serotonin Reuptake Inhibitor (SSRI) Antidepressant Treatment [PDF]
Mental health issues, especially depressive disorders, are major burdens to the health care systems. This has been more pronounced since the onset of the COVID-19 pandemic.
Huijuan Liao+2 more
doaj +2 more sources
Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine. [PDF]
V. Stearns+8 more
semanticscholar +2 more sources
Key Points Question Are selective serotonin reuptake inhibitors (SSRIs), specifically fluoxetine hydrochloride, associated with a lower mortality risk among patients with COVID-19?
T. Oskotsky+7 more
semanticscholar +1 more source
Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model. [PDF]
Multimodal analgesia is designed to optimize pain relief by coadministering drugs with distinct mechanisms of action or by combining multiple pharmacologies within a single molecule. In clinical settings, combinations of monoamine reuptake inhibitors and
Fei Shen+4 more
doaj +1 more source
The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2
To circumvent time-consuming clinical trials, testing whether existing drugs are effective inhibitors of SARS-CoV-2, has led to the discovery of Remdesivir.
M. Zimniak+4 more
semanticscholar +1 more source
Carcinoid heart disease is a complication of carcinoid syndrome. The role of selective serotonin reuptake inhibitors in carcinoid heart disease is unclear. We present a case of refractory heart failure due to right- and left-sided carcinoid heart disease
Jennifer Bell, MD+4 more
doaj +1 more source
The serotonin transporter (SERT) is the primary target for selective serotonin reuptake inhibitor (SSRI) antidepressants that are thought to exert their therapeutic effects by increasing the synaptic concentration of serotonin.
Ian D. Tomlinson+11 more
doaj +1 more source
Selective Serotonin Reuptake Inhibitor Pharmaco-Omics: Mechanisms and Prediction
Selective serotonin reuptake inhibitors (SSRIs) are a standard of care for the pharmacotherapy of patients suffering from Major Depressive Disorder (MDD). However, only one-half to two-thirds of MDD patients respond to SSRI therapy. Recently, a “multiple
Thanh Thanh L. Nguyen+5 more
doaj +1 more source