Results 11 to 20 of about 117,536 (400)
Serotonin reuptake inhibitors and cardiovascular disease [PDF]
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R.+2 more
core +4 more sources
Selective serotonin reuptake inhibitors [PDF]
The increasing use of antidepressants—particularly the selective serotonin reuptake inhibitors (SSRIs)—might be grounds for optimism because it might indicate that one of the great health problems of our age is increasingly being recognised and treated. Instead SSRIs have become embroiled in controversy over both their effectiveness and safety. As well
Geddes J., CIPRIANI, Andrea
openaire +6 more sources
Dosing of Selective Serotonin Reuptake Inhibitors [PDF]
Sir: I am writing to address an inaccuracy written about the dosing and administration of selective serotonin reuptake inhibitor (SSRI) medications in the article by Marken and Munro published in the December 2000 issue of the Companion.1 Contrary to the contention by Drs. Marken and Munro that sertraline is more effective at the high end of the dosage
Henry Chung
openalex +4 more sources
Sentiment Analysis of Online Reviews for Selective Serotonin Reuptake Inhibitors and Serotonin–Norepinephrine Reuptake Inhibitors [PDF]
Background: Depression affects millions worldwide, with drug therapy being the mainstay treatment. A variety of factors, including personal reviews, are involved in the success or failure of medication therapy. This study looked to characterize the sentiment of online medication reviews of Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin ...
Chad Compagner+2 more
openaire +4 more sources
Background Serotonin toxicity is a known side effect of selective serotonin reuptake inhibitors and has previously also been described as a possible side effect of 5-hydroxytryptamine receptor agonist (triptan) medications.
Gilbert Jin, Philip Stokes
doaj +1 more source
The pharmacogenomics of selective serotonin reuptake inhibitors [PDF]
The introduction of selective serotonin (5-HT) reuptake inhibitors (SSRIs) has significantly improved the pharmacological treatment of a range of psychiatric disorders. Nevertheless, despite the undoubted advantages of antidepressant treatment in terms of improved tolerability to therapy while maintaining a high level of efficacy, not all patients ...
SERRETTI, ALESSANDRO, Artioli P.
openaire +4 more sources
Selective serotonin reuptake inhibitors in the treatment of generalized anxiety disorder [PDF]
Selective serotonin reuptake inhibitors have proven efficacy in the treatment of panic disorder, obsessive–compulsive disorder, post-traumatic stress disorder and social anxiety disorder.
Allgulander C+41 more
core +1 more source
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose
We aimed to investigate the frequency of serotonin toxicity following overdose of antidepressants that inhibit serotonin reuptake and the factors that influence the probability of serotonin toxicity occurring. This was a retrospective cohort study of overdoses that included selective serotonin reuptake inhibitors (SSRIs) (70%) and serotonin ...
Joyce Cooper+2 more
openaire +3 more sources
Pharmacological Characterization of Toludesvenlafaxine as a Triple Reuptake Inhibitor
Toludesvenlafaxine hydrochloride dihydrate is a novel chemical entity and a potential triple monoamine reuptake inhibitor. This study characterized the in vitro triple reuptake inhibition activity, antidepressant-like activity in animals, and ...
Haibo Zhu+9 more
doaj +1 more source