Results 221 to 230 of about 42,502 (303)

Pregabalin dependence, withdrawal, suicidality and psychosis reports: A disproportionality analysis of the Australian adverse events database

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 545-555, February 2026.
Aims Globally, Australia has the highest per capita consumption rate of pregabalin, commonly prescribed for neuropathic pain. Emerging evidence suggests pregabalin may be associated with the onset or recurrence of several potentially life‐threatening psychiatric events in some individuals.
Amy G. McNeilage   +4 more
wiley   +1 more source

From Struggling (With) Screening Tests to Mouse Models of Depression‐Relevant Neurobehavioral States

open access: yesCurrent Protocols, Volume 6, Issue 2, February 2026.
Abstract A major, serendipitous psychiatric discovery is monoamine‐transporter reuptake inhibition as an antidepressant mechanism of action. Chronic treatment with such antidepressants is efficacious, with onset requiring 1‐2 weeks, in many but by no means all patients with major depressive or another stress‐related neuropsychiatric disorder.
Christopher R. Pryce
wiley   +1 more source

Development and Validation of the Brief Inventory of Treatment Expectations in Chronic Pain (BITEC)

open access: yesEuropean Journal of Pain, Volume 30, Issue 2, February 2026.
ABSTRACT Background Expectations shape therapeutic outcomes, yet their systematic assessment remains limited in clinical and research settings. To address this gap, we developed and validated the Brief Instrument for the Assessment of Treatment Expectations in Chronic Pain (BITEC) using Item Response Theory. Methods The study comprised four phases. (I)
Wolnei Caumo   +8 more
wiley   +1 more source

The selective serotonin reuptake inhibitor paroxetine improves right ventricular systolic function in experimental pulmonary hypertension. [PDF]

open access: yesJ Mol Cell Cardiol Plus
Waddingham MT   +7 more
europepmc   +1 more source

Molecular and Transcriptional Signatures of Gray Matter Volume Alterations Associated With Depressive Symptoms in Mild Cognitive Impairment

open access: yesHuman Brain Mapping, Volume 47, Issue 2, February 1, 2026.
Morphological alterations related to depressive symptoms in mild cognitive impairment were primarily involved in emotion and affective processing, showing strong correspondence with serotonergic, dopaminergic, and GABAergic systems and enrichment of genes associated with synaptic function and excitatory neurons.
Hu Xu   +9 more
wiley   +1 more source

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