Results 41 to 50 of about 117,536 (400)

Selective serotonin reuptake inhibitor prescribing before, during and after pregnancy: a population‐based study in six European regions

open access: yesBJOG: an International Journal of Obstetrics and Gynaecology, 2015
To explore the prescribing patterns of selective serotonin reuptake inhibitors (SSRIs) before, during and after pregnancy in six European population‐based databases.
Rachel A. Charlton   +14 more
semanticscholar   +1 more source

The genetics of selective serotonin reuptake inhibitors

open access: yesPharmacology & Therapeutics, 2012
Selective serotonin reuptake inhibitors (SSRIs) are among the most widely prescribed drugs in psychiatry. Based on the fact that SSRIs increase extracellular monoamine levels in the brain, the monoamine hypothesis of depression was introduced, postulating that depression is associated with too low serotonin, dopamine and noradrenaline levels.
Yvet Kroeze   +3 more
openaire   +4 more sources

Switching antidepressants

open access: yesSouth African Family Practice, 2015
Switching antidepressants because of lack of efficacy or unacceptable side effects, while often required in general practice, may result in toxic drug-drug interactions, worsening depression or unpleasant discontinuation reactions.
K. Outhoff
doaj   +1 more source

Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A meta-analysis of randomised controlled treatment trials [PDF]

open access: yes, 2006
Small studies have shown positive effects from adding a variety of antipsychotic agents in patients with obsessive–compulsive disorder who are unresponsive to treatment with serotonin reuptake inhibitors. The evidence, however, is contradictory.
Carey, P   +8 more
core   +1 more source

Selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors in pregnancy: Infant and childhood outcomes [PDF]

open access: yesPaediatrics & Child Health, 2021
Abstract This position statement provides guidance for the monitoring, care, and follow-up of newborns exposed to selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) in utero. Depression and anxiety are common during pregnancy and postpartum.
Leonora Hendson   +2 more
openaire   +3 more sources

Risk of suicide during treatment with venlafaxine, italopram, fluoxetine, and dothiepin : retrospective cohort study [PDF]

open access: yes, 2006
Objective To compare the risk of suicide in adults usingthe antidepressant venlafaxine compared with citalopram, fluoxetine, and dothiepin. Design Retrospective cohort study. Setting UK General Practice Research Database. Participants 219 088 patients,
Andrews, Elizabeth   +5 more
core   +2 more sources

A randomised, double-blind study in adults with major depressive disorder with an inadequate response to a single course of selective serotonin reuptake inhibitor or serotonin–noradrenaline reuptake inhibitor treatment switched to vortioxetine or agomelatine

open access: yesHuman psychopharmacology, 2014
This randomised, double‐blind, 12‐week study compared efficacy and tolerability of flexible‐dose treatment with vortioxetine (10–20 mg/day) versus agomelatine (25–50 mg/day) in major depressive disorder patients with inadequate response to selective ...
S. Montgomery   +3 more
semanticscholar   +1 more source

Duloxetine-induced rapid eye movement sleep behavior disorder: a case report

open access: yesBMC Psychiatry, 2017
Background Tricyclic antidepressants and selective serotonin reuptake inhibitors have been reported to induce the symptoms of rapid eye movement (REM) sleep behavior disorder (RBD) or to exacerbate REM sleep without atonia.
Lu Tan   +6 more
doaj   +1 more source

A Neurobiological Hypothesis of Treatment-Resistant Depression – Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy

open access: yesFrontiers in Behavioral Neuroscience, 2014
First-line treatment of major depression includes administration of a selective serotonin reuptake inhibitor (SSRI), yet studies suggest that remission rates following two trials of an SSRI are
J. Coplan   +3 more
semanticscholar   +1 more source

Imidazoles as Serotonin Receptor Modulators for Treatment of Depression: Structural Insights and Structure–Activity Relationship Studies

open access: yesPharmaceutics, 2023
Serotoninergic signaling is identified as a crucial player in psychiatric disorders (notably depression), presenting it as a significant therapeutic target for treating such conditions.
Kapil Kumar Goel   +5 more
doaj   +1 more source

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