Results 211 to 220 of about 141,303 (265)

Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics

The Journal of Physiology, EarlyView.
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana, Collin Matsumoto, L. Fernando Santana   +2 more
wiley   +1 more source

Prophage-mediated lysogenic conversion drives virulence evolution and genomic plasticity in <i>Streptococcus suis</i> serotype 9. [PDF]

Microbiol Spectr
Wen Z, Guo Y, Liang Y, Li Y, Lian K, Tang R, Li S, Zheng P, Qu Y.   +8 more
europepmc   +1 more source

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source

Establishment and optimization of an <i>E. coli</i> urinary tract infection model in Göttingen minipigs with strain recovery and characterization. [PDF]

Front Immunol
Lübbers J, Orlandini K, Podob E, Fernandez J, Wilson JM, van Heerden M, Zeijpveld J, van Kregten J, Buckley PT, van den Dobbelsteen G, Bair KL.   +10 more
europepmc   +1 more source

What is driving the resurgence and persistence of vaccine-targeted pneumococcal serotypes?-Serotype 19F as the paradigm. [PDF]

PLoS Pathog
Thindwa D, Carcamo PM, Dagan R, Weinberger DM.   +3 more
europepmc   +1 more source

Long-term antibody dynamics challenge the paradigm of lifelong homotypic immunity to dengue virus. [PDF]

Proc Natl Acad Sci U S A
Andrade J, Mitard de Girardier A, Huang AT, Buddhari D, Hamins-Puertolas M, Alera MT, Chua MN, Hunsawong T, Cummings DAT, Thomas S, Friberg H, Currier JR, Waickman A, Farmer A, Yoon IK, Anderson K, Rothman AL, Salje H.   +17 more
europepmc   +1 more source

Induction of Salivary IgA and IgG Responses by Parenteral PPV23 Vaccination in Older Adults. [PDF]

Open Forum Infect Dis
Visser M, Tcherniaeva I, de Rond L, de Zeeuw-Brouwer ML, Verschuren MWM, Picavet SHSJ, de Jonge MI, den Hartog G, Buisman AM.   +8 more
europepmc   +1 more source

Pneumococci detected in sterile body fluids of pediatric patients postpandemic trends from a single center. [PDF]

Antimicrob Steward Healthc Epidemiol
Üstündağ G, Karadağ Öncel E, Şahin A, Elvan Tüz A, Ekemen Keleş Y, Taşar Karabulut S, Ağralı Eröz N, Doğan G, Yılmaz D, Yılmaz N, Hasçelik G, Ceyhan M.   +11 more
europepmc   +1 more source

Invasive Pneumococcal Disease Epidemiology and Conjugate Vaccines in Canada, 2000-2019.

JAMA Netw Open
Ramos B, Vadlamudi NK, Golden AR, Martin I, Tyrrell G, Brousseau N, Sadarangani M, Canadian Immunization Research Network.   +7 more
europepmc   +1 more source