Results 301 to 310 of about 225,179 (344)

Astroglial CB1 Reveal Sex‐Specific Synaptic Effects of Amphetamine

Glia, Volume 73, Issue 8, Page 1673-1691, August 2025.
Main Points Astroglial CB1 mediate long‐term depression in the NAc through purine release. Amphetamine occludes LTD in male mice by inducing the saturation of A1 receptors. Astroglial CB1 mediate behavioral amphetamine effects in males, but not in females.
Yamuna Mariani, Tommaso Dalla‐Tor, Tommaso Garavaldi, Francisca Julio‐Kalajzić, Doriane Gisquet, Paula Gomez‐Sotres, Astrid Cannich, Giuditta Gambino, Filippo Drago, Roman Serrat, Imane Hurel, Francis Chaouloff, Sandrine Pouvreau, Luigi Bellocchio, Giovanni Marsicano, Ana Covelo   +15 more
wiley   +1 more source

Age-related decline in IgM responses associate with reduced opsonophagocytic activity following PCV13 vaccination. [PDF]

NPJ Vaccines
Visser M, van Beek J, Tcherniaeva I, van Rooijen DM, Beckers L, Bijvank E, de Jonge MI, Lockhart SP, Pride MW, Rots N, van Baarle D, den Hartog G, Buisman AM.   +12 more
europepmc   +1 more source

Temporal Trends in Cardiovascular Mortality in Underlying Viral Hepatitis: A Retrospective Analysis of Gender, Racial/Ethnic, and Regional Disparities

JGH Open, Volume 9, Issue 8, August 2025.
ABSTRACT Objective This study aimed to investigate contemporary trends in mortality related to cardiovascular disease and viral hepatitis. Methods We conducted a retrospective analysis using data from the CDC‐WONDER dataset. Our study cohort consisted of adults aged ≥ 15 years, where both cardiovascular disease and viral hepatitis were identified as an
Wania Sultan, Haider Ashfaq, Hamza Ashraf, Ahmad Khan, Ayman Omair Hashmi, Muhammad Omar Larik, Maheen Zahid, Yasir Majeed, Pratik Bhattarai, Ashujot K. Dang, Ahmed Ali Aziz, Hafiz Muhammad Sharjeel Arshad   +11 more
wiley   +1 more source

Annual global dengue dynamics are related to multi-source factors revealed by a machine learning prediction analysis. [PDF]

PLoS Negl Trop Dis
Long H, Chen Y, Feng J, Chen J, Zhang X, Han W, Kang M, Du X.   +7 more
europepmc   +1 more source

Risk Stratification of Dengue Cases Requiring Hospitalization

Journal of Medical Virology, Volume 97, Issue 8, August 2025.
ABSTRACT Dengue pathogenesis involves immune‐driven inflammation that contributes to severe disease progression. This study assessed a machine learning model to identify a minimal, yet highly predictive biomarker set, aiming to support clinical decision‐making and patient triage.
Do Duc Anh, Mario Recker, Nguyen Trong The, Sanjeev Krishna, Peter G. Kremsner, Le Huu Song, Thirumalaisamy P. Velavan   +6 more
wiley   +1 more source

Evaluation of Streptococcus pneumoniae as a cause of acute otitis media in Colombia: A prospective study. [PDF]

PLoS One
Coronell-Rodriguez W, Camerano R, Alvarado-Gonzalez JC, Puerto A, Zakzuk J, Alvis-Zakzuk NR, Moyano-Tamara L, Medina S, Beltran C, Betancur M, Rojas M, Farias LE, Pinzon-Redondo H, Villamor P, Osorio S, Alvis-Guzmán N.   +15 more
europepmc   +1 more source

Prevalence of Antimicrobial Resistance in Klebsiella pneumoniae in the South African Populations: A Systematic Review and Meta‐Analysis of Surveillance Studies

MicrobiologyOpen, Volume 14, Issue 4, August 2025.
Klebsiella pneumoniae isolates in South Africa exhibit > 50% resistance to first‐line antibiotics, with rising carbapenem resistance. Urgent, targeted interventions and genomic surveillance are essential to curb the spread of multidrug‐resistant strains and preserve treatment efficacy.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Epigenetic changes and serotype-specific responses of alveolar type II epithelial cells to Streptococcus pneumoniae in resolving influenza A virus infection. [PDF]

Cell Commun Signal
Boehme JD, Jeron A, Schultz K, Melcher L, Schott K, Gelmez E, Kröger A, Stegemann-Koniszewski S, Bruder D.   +8 more
europepmc   +1 more source

Peptide Drug: Design and Clinical Applications

MedComm, Volume 6, Issue 8, August 2025.
The diagram illustrates the role of poly peptides in various biological processes. It highlights their involvement in glucose, lipid, and amino acid metabolism, as well as in antitumor and antiviral immunity. Additionally, poly peptides are linked to disease diagnosis and prognosis, emphasizing their significance in healthcare.
Yaqi Han, YunKui Zhang, Han Li, Zhongliang Ma, Yanmao Wang   +4 more
wiley   +1 more source

Post-vaccination Streptococcus pneumoniae colonization and respiratory manifestations in children: A prospective cohort study. [PDF]

PLoS One
Benedetti JEV, Pizzutti K, Mott MP, Vieira PUP, Bruscato NM, Moriguchi EH, Dalla Corte RR, Santana JCB, Dias C.   +8 more
europepmc   +1 more source