Results 21 to 30 of about 118,912 (188)

Circumventing antivector immunity: potential use of nonhuman adenoviral vectors [PDF]

, 2014
Adenoviruses are efficient gene delivery vectors based on their ability to transduce a wide variety of cell types and drive high-level transient transgene expression. While there have been advances in modifying human adenoviral (HAdV) vectors to increase
Beard C.W., Benkö M., Cauthen A.N., Crawford-Miksza L., Estrella Lopez-Gordo, Gall J., Gall J.G., Gattoni A., Ginsberg H.S., Haviv Y.S., Hofmann C., Iva I. Podgorski, Kajon A.E., Kanerva A., Kass-Eisler A., Kuriyama S., Mastrangeli A., Michou A.I., Nicholas Downes, Ramon Alemany, Rogozhin V.N., Roy S., Seiradake E., Shmarov M.M., Soudais C., Tutykhina I.L., Wang D.Y., Wohlfart C., Ying B., Zakhartchouk A.N., Zeng Q.   +30 more
core   +3 more sources

Development and evaluation of serotype-specific recombinase polymerase amplification combined with lateral flow dipstick assays for the diagnosis of foot-and-mouth disease virus serotype A, O and Asia1

BMC Veterinary Research, 2018
Background Foot-and-mouth disease (FMD) caused by foot-and-mouth disease virus (FMDV) is one of the most highly infectious diseases in livestock, and leads to huge economic losses.
Hongmei Wang, Peili Hou, Guimin Zhao, Li Yu, Yu-wei Gao, Hongbin He   +5 more
doaj   +1 more source

Serotype-specific glycoprotein of simian 11 rotavirus: coding assignment and gene sequence. [PDF]

Proceedings of the National Academy of Sciences, 1983
Cloned DNA copies of the double-stranded RNA genomic segments of simian 11 rotavirus have been used to determine the coding assignment for VP7, the type-specific antigen of this virus. Translation of hybrid-selected mRNAs in an in vitro system supplemented with canine pancreatic microsomes permitted VP7 to be assigned to segment 9 and the two ...
G W, Both, J S, Mattick, A R, Bellamy
openaire   +2 more sources

Streptococcus infantis, Streptococcus mitis, and Streptococcus oralis Strains With Highly Similar cps5 Loci and Antigenic Relatedness to Serotype 5 Pneumococci

Frontiers in Microbiology, 2019
Streptococcus pneumoniae is a highly impactful bacterial pathogen on a global scale. The principal pneumococcal virulence factor and target of effective vaccines is its polysaccharide capsule, of which there are many structurally distinct forms. Here, we
Fabiana Pimenta, Robert E. Gertz, So Hee Park, Ellie Kim, Iaci Moura, Jennifer Milucky, Nadine Rouphael, Monica M. Farley, Monica M. Farley, Lee H. Harrison, Nancy M. Bennett, Godfrey Bigogo, Godfrey Bigogo, Daniel R. Feikin, Daniel R. Feikin, Robert Breiman, Robert Breiman, Fernanda C. Lessa, Cynthia G. Whitney, Gowrisankar Rajam, Jarad Schiffer, Maria da Gloria Carvalho, Bernard Beall   +22 more
doaj   +1 more source

Molecular characterization of foot-and-mouth disease viruses collected from Northern and Central Ethiopia during the 2018 outbreak [PDF]

Veterinary World, 2020
Background and Aim: Foot-and-mouth disease (FMD) is endemic in several developing countries and affects poor farmers through loss of production, death of diseased animals, and loss of animal byproducts. Forty-three samples were collected from 12 sites of
Yeneneh Tesfaye, Fazlurrahman Khan, Esayas Gelaye   +2 more
doaj   +1 more source

Human streptococcus agalactiae strains in aquatic mammals and fish [PDF]

, 2013
<p>Background: In humans, Streptococcus agalactiae or group B streptococcus (GBS) is a frequent coloniser of the rectovaginal tract, a major cause of neonatal infectious disease and an emerging cause of disease in non-pregnant adults.
Crumlish, M., Dagleish, M.P., Delannoy, C.M.J., Fontaine, M.C., Foster, G., Pollock, J., Turnbull, J.F., Zadoks, R.N.   +7 more
core   +5 more sources

Multiplexing AAV Serotype-Specific Neutralizing Antibodies in Preclinical Animal Models and Humans

Biomedicines, 2023
The accurate assessment of AAV-specific pre-existing humoral immunity due to natural viral infection is critical for the efficient use of clinical gene therapy. The method described in the present study applies equivalent infection conditions to each AAV
Hisae Kuoch, Karina Krotova, Melanie L. Graham, Mark L. Brantly, George Aslanidi   +4 more
doaj   +1 more source

Targeting of putative fimbrial gene for detection of S. Typhi in typhoid fever and chronic typhoid carriers by nested PCR

Journal of Infection in Developing Countries, 2013
Introduction: It is important to identify Salmonella Typhi infection quickly to treat acute fever patients and to prevent transmission by chronic typhoid carriers; therefore, a very specific and sensitive diagnostic technique is highly desirable ...
Chandra Bhan Pratap, Gopal Kumar, Saurabh Kumar Patel, Ajay Kumar Verma, Vijay K Shukla, Kailash Kumar, Gopal Nath   +6 more
doaj   +1 more source

Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection [PDF]

, 2013
Streptococcus pneumoniae of serotype 3 possess a mucoid capsule and cause disease associated with high mortality rates relative to other pneumococci. Phylogenetic analysis of a complete reference genome and 81 draft sequences from clonal complex 180, the
Barquist, L, Bentley, SD, Browall, S, Croucher, NJ, Dordel, J, Feltwell, T, Fookes, MC, Gould, KA, Harris, SR, Henriques-Normark, B, Hinds, J, Inverarity, D, Mitchell, AM, Mitchell, TJ, Normark, S, Parkhill, J, Salter, SJ, Zemlickova, H   +17 more
core   +4 more sources

Capsular polysaccharide determines the serotyping of Riemerella anatipestifer

Microbiology Spectrum, 2023
Riemerella anatipestifer (R. anatipestifer) is a Gram-negative pathogen that causes significant economic losses to the farming industry. The polysaccharides that determine serotype are well understood in other bacteria; they have not yet been fully ...
Yanling Liu, Shuxin Luo, Zhishuang Yang, Mingshu Wang, Renyong Jia, Shun Chen, Mafeng Liu, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Xumin Ou, Sai Mao, Qun Gao, Di Sun, Bin Tian, Anchun Cheng, Dekang Zhu   +18 more
doaj   +1 more source