Results 161 to 170 of about 155,234 (391)
Optimal Serotype Compositions for Pneumococcal Conjugate Vaccination under Serotype Replacement
PLoS Computational Biology, 2014 Pneumococcal conjugate vaccination has proved highly effective in eliminating vaccine-type pneumococcal carriage and disease. However, the potential adverse effects of serotype replacement remain a major concern when implementing routine childhood pneumococcal conjugate vaccination programmes.
Auranen Kari, Nurhonen Markku
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AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics
Advanced Intelligent Systems, EarlyView.This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee +3 more
wiley +1 more source
Genotypic Characterization of Non-O157 Shiga Toxin–Producing Escherichia coli in Beef Abattoirs of Argentina [PDF]
, 2011 The non-O157 Shiga toxin-producing Escherichia coli (STEC) contamination in carcasses and feces of 811 bovines in nine beef abattoirs from Argentina was analyzed during a period of 17 months.
Carbonari, Claudia Carolina +9 more
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Molecular dynamics of the host response to Streptococcus pneumoniae pneumonia in baboons
Animal Models and Experimental Medicine, EarlyView.Using an established, clinically relevant nonhuman primate model of S. pneumoniae pneumonia, this study aims to identify novel potential molecular diagnostic and therapeutic targets using peripheral blood bulk transcriptomic, unbiased proteomic, and cytokine measurements. The constructed models were highly accurate in classifying bacterial pneumonia in
Bryan D. Kraft +18 more
wiley +1 more source
Indian Journal of Pathology and Microbiology, 2016 Background: Dengue virus serotyping is crucial from clinical management and epidemiological point of view. Aims: To compare efficacy of two molecular detection and typing methods, namely, multiplex reverse transcription polymerase chain reaction (RT-PCR)
Anita Chakravarti +3 more
doaj +1 more source
Salmonella enterica subsp. enterica along the pig commodity chain in Vietnam [PDF]
, 2008 Foodborne diseases are a particularly important concern in the current Vietnamese context, shortly after accession to the WTO, not only for public health reasons, but also because of the global evolution of consumer demand and habits, the production ...
Bily, L. +14 more
core
Annals of Neurology, EarlyView.Objective Myotonic dystrophy type 1 (DM1) is a highly variable, multisystemic genetic disorder caused by a CTG repeat expansion in the 3′ untranslated region of DMPK. Toxicity is exerted by repeat‐containing DMPK transcripts that sequester muscleblind‐like (MBNL) proteins and lead to deleterious yet predictable changes in alternative splicing.
Samuel T. Carrell +3 more
wiley +1 more source
Progressive Changes of Vibrio Serotypes in Germ-free Mice Infected withVibrio cholerae [PDF]
, 1969 R. Bradley Sack, Carl E. Miller
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The complexity of serotype replacement of pneumococci [PDF]
Human Vaccines & Immunotherapeutics, 2019 Pneumococci respond extremely rapidly to the vaccine pressure created by the conjugate vaccines (PCVs). Vaccine serotypes are disappearing, meanwhile new, often previously very rare types are emerging, and it is difficult to establish what makes certain serotypes more successful in replacement.
openaire +4 more sources