Final Analysis of the Phase 1/2 Trial of Valoctocogene Roxaparvovec for Severe Haemophilia A
ABSTRACT Introduction Valoctocogene roxaparvovec is an adeno‐associated virus vector serotype 5 (AAV5)‐mediated gene therapy for severe haemophilia A (HA). Aim Report the final safety and efficacy results of the phase 1/2 trial of valoctocogene roxaparvovec. Methods An open‐label phase 1/2 trial (NCT02576795) enrolled adult males with severe HA (factor
Priyanka Raheja +9 more
wiley +1 more source
Integrated analysis of MALDI-TOF MS and whole-genome sequencing for subtyping <i>Salmonella</i>. [PDF]
Liu Y, Qiao J, Xiao Y, Zhang T, Wu Y.
europepmc +1 more source
Circulating Dengue Serotypes in Sandakan and Kudat districts of Sabah: during 2016 to 2017 [PDF]
Timothy Jr Gintarong
openalex
Cloning and nucleotide sequence of the eae gene homologue from enterohemorrhagic Escherichia coli serotype O157:H7 [PDF]
Glen Beebakhee
openalex +1 more source
Considerations for the Use of AAV‐based Gene Therapy in HIV‐Positive Individuals With Haemophilia
ABSTRACT Introduction There is a high prevalence of human immunodeficiency virus (HIV) infection among the haemophilia community due to treatment in the 1970s and 1980s with contaminated clotting factor. Lifelong treatment regimens for haemophilia and HIV are burdensome alone and pose a particular challenge for individuals living with both conditions ...
Jürgen K. Rockstroh +5 more
wiley +1 more source
Bacterial Profile, Molecular Serotyping, and Key Genetic Determinants for Adhesion, Immune Evasion, and Tissue Spread Among Bulgarian Children with Acute Otitis Media. [PDF]
Alexandrova AS, Boyanov VS, Gergova RT.
europepmc +1 more source
Diadenylate cyclase evaluation of ssDacA (SSU98_1483) in Streptococcus suis serotype 2
Dirk U. Bellstedt, Jianhe Sun
openalex +1 more source
Molecular Analysis of the Genetic Variation among Penicillin‐Susceptible and Penicillin‐ResistantStreptococcus pneumoniaeSerotypes in Canada [PDF]
Marie Louie +5 more
openalex +1 more source

