Results 231 to 240 of about 42,797 (295)

Serotype specific qRT-PCR for novel BTV serotypes

open access: yes
D5.1: Serotype specific qRT-PCR for novel BTV serotypes (Partner 1, 2, 4, 5, 12, 16). (M18)
openaire   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan   +19 more
wiley   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi   +11 more
wiley   +1 more source

Whole-genome sequencing-based pathogen characterization for streptococcal infection directly from positive blood culture samples. [PDF]

open access: yesJ Clin Microbiol
Li Y   +11 more
europepmc   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

open access: yesAdvanced Science, Volume 13, Issue 17, 23 March 2026.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li   +11 more
wiley   +1 more source

Identification of a new Salmonella serovar - Salmonella Scharmann (8:z41:1,5). [PDF]

open access: yesGMS Infect Dis
Téllez-Castillo CJ   +4 more
europepmc   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song   +11 more
wiley   +1 more source

The sero-prevalence and virulence determinants of <i>Klebsiella pneumoniae</i> isolated from urine in outpatient units: a 20-year collection from Taiwan as a herald for serotype vaccine selection. [PDF]

open access: yesMicrobiol Spectr
Chiu S-K   +10 more
europepmc   +1 more source

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