Abstract Epilepsy affects approximately 1% of the population worldwide, and although medications are effective in the majority of cases, seizures persist in approximately 30% of patients. Despite the effort to develop new antiseizure drugs, the rate of pharmacoresistance in patients has not diminished over the past 3 decades. There is thus a real unmet
Vincent Magloire+9 more
wiley +1 more source
Field validation and application of the luminex triplex HIV assay to estimate HIV prevalence and HIV-1 incidence in Nigeria. [PDF]
Yufenyuy EL+26 more
europepmc +1 more source
Polypeptide patterns of infectious bronchitis virus serotypes fall into two categories [PDF]
Éva Nagy, B. Lomniczi
openalex +1 more source
Molecular detection of pathogens in an equine fever diagnostic panel: 2019–2023
Abstract Background A common diagnostic approach for febrile horses is to test for a panel of potential pathogens. Panels are curated by expert opinion and vary between diagnostic laboratories. Objectives To report the results of a newly developed equine fever diagnostic panel (EFDP) between 2019 and 2023 and evaluate the frequency of positive results.
Toby L. Pinn‐Woodcock+3 more
wiley +1 more source
Automated identification of <i>Salmonella</i> serotype using MALDI-TOF mass spectrometry and machine learning techniques. [PDF]
Ren J+9 more
europepmc +1 more source
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik+2 more
wiley +1 more source
Surveillance of <i>Salmonella</i> Serovars in the Food Chain in Poland: A Five-Year Review (2016-2020). [PDF]
Skrzypiec E+13 more
europepmc +1 more source
Serological Examination of Some Strains That Are in the Mycobacterium avium-intracellulare-scrofulaceum Complex But Do Not Belong to Schaefer's Serotypes [PDF]
M. Reznikov, David J. Dawson
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Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder+4 more
wiley +1 more source