Results 31 to 40 of about 68,760 (263)
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Frontiers in Microbiology, 2017 The ubiquitous and opportunistic pathogen Cronobacter sakazakii is responsible for severe meningitis, sepsis, and necrotizing enterocolitis in neonates and infants associated with ingestion of contaminated powdered infant formula (PIF).
Eva J. Scharinger +4 more
doaj +1 more source
Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types [PDF]
, 2011 We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland.
Andrew Smith +24 more
core +3 more sources
Microbiology Spectrum, 2023 In this study, we selected bacteremic Klebsiella pneumoniae isolates from the Taiwan Surveillance of Antimicrobial Resistance program. A total of 521 isolates were collected over a period of 2 decades, including 121 from 1998, 197 from 2008, and 203 from
Chun-Chou Tsai +11 more
doaj +1 more source
Genomic relatedness within five common Finnish Campylobacter jejuni pulsed-field gel electrophoresis genotypes studied by amplified fragment length polymorphism analysis, ribotyping and serotyping [PDF]
, 2001 Thirty-five Finnish Campylobacter jejuni strains with five SmaI/SacII pulsed-field gel electrophoresis (PFGE) genotypes selected among human and chicken isolates from 1997 and 1998 were used for comparison of their PFGE patterns, amplified fragment ...
Duim, B. +4 more
core +3 more sources
Frontiers in Microbiology, 2020 Whole-genome sequencing (WGS) is used increasingly in public-health laboratories for typing and characterizing foodborne pathogens. To evaluate the performance of existing bioinformatic tools for in silico prediction of antimicrobial resistance (AMR) and
Ashley L. Cooper +10 more
doaj +1 more source
Антибиотики и Химиотерапия, 2022 The paper presents optimized methods for PCR and sequence typing of Streptococcus pneumoniae. The serotype composition of pneumococci isolated from children under 5 years of age with infections of the upper respiratory tract was analyzed using optimized ...
E. V. Nikitina +9 more
doaj +1 more source
Systems Biology and Pangenome of Salmonella O-Antigens. [PDF]
, 2019 O-antigens are glycopolymers in lipopolysaccharides expressed on the cell surface of Gram-negative bacteria. Variability in the O-antigen structure constitutes the basis for the establishment of the serotyping schema. We pursued a two-pronged approach to
Kavvas, Erol +4 more
core +2 more sources
Assessment and Comparison of Molecular Subtyping and Characterization Methods for Salmonella
Frontiers in Microbiology, 2019 The food industry is facing a major transition regarding methods for confirmation, characterization, and subtyping of Salmonella. Whole-genome sequencing (WGS) is rapidly becoming both the method of choice and the gold standard for Salmonella subtyping ...
Silin Tang +7 more
doaj +1 more source
Serotyping of Toxoplasma gondii Infection Using Peptide Membrane Arrays. [PDF]
, 2019 The intracellular parasite Toxoplasma gondii can cause chronic infections in most warm-blooded animals, including humans. In the USA, strains belonging to four different Toxoplasma clonal lineages (types 1, 2, 3, and 12) are commonly isolated, whereas ...
Arranz-Solís, David +6 more
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