Results 11 to 20 of about 56,601 (164)
Similar to the already well-recognized adenoma-carcinoma sequence in colorectal cancer pathogenesis, it has been believed for many decades that the progression of ovarian epithelial tumors occurs from benign serous cystadenomas to borderline tumors, to ...
Tiberiu-Augustin Georgescu +5 more
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Uterine Papillary Serous Carcinoma [PDF]
Uterine papillary serous carcinoma (UPSC) is a histologic variant of endometrial cancer that accounts for only 10% of new cases of uterine cancer but is responsible for 40% of deaths from the disease. UPSC is an aggressive tumor with a predilection for early spread beyond the uterus.
Kathleen N, Moore, Amanda Nickles, Fader
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Serous endometrial cancer represents a relative rare entity accounting for about 10% of all diagnosed endometrial cancer, but it is responsible for 40% of endometrial cancer-related deaths. Patients with serous endometrial cancer are often diagnosed at earlier disease stage, but remain at higher risk of recurrence and poorer prognosis when compared ...
Bogani G. +31 more
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Serous tubal intraepithelial carcinoma is a precursor lesion for high-grade pelvic serous carcinoma. The incidence is 0.6%–6% in tubectomy specimens of women who are BRCA-1,2 positive or have a strong family history of breast or ovarian cancer.
Shirish Sahebrao Chandanwale +3 more
doaj +1 more source
Summary: Low-grade and high-grade serous carcinomas have unique clinical, morphological, underlying molecular alterations, and vastly different biologic behavior (Prat et al., 2018, Vang et al., 2009).
Shivali Marketkar +2 more
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Sarcomatoid or anaplastic carcinomas arising within epithelial ovarian neoplasms are rare, particularly within serous tumors of the ovary, and carry a poor prognosis. Here we present the case of a patient initially diagnosed with low grade serous ovarian
Paulina Haight +2 more
doaj +1 more source
High-grade versus low-grade serous carcinoma of the ovary – current differential diagnosis and perspectives [PDF]
Introduction. Serous carcinoma is responsible for 47% of all ovarian cancers, and from these cases, only 5% are represented by low-grade serous carcinoma, the rest of them accounting for high-grade serous carcinoma. Objective. The aim of this study is
Manuela POPA +4 more
doaj +1 more source
Immunohistochemical Expression of Flotillin1in Ovarian Serous Carcinoma [PDF]
Background: Ovarian cancer is one of the most common cancers among females worldwide. Its pathogenesis is not well understood till now. FLOT-1 is expressed in a wide range of normal and neoplastic tissues and has emerged as an important regulator ...
Maram El-Hussieny +3 more
doaj +1 more source
Background High-grade serous ovarian carcinoma is highly heterogeneous, and although many studies have been conducted to identify high-grade serous ovarian carcinoma molecular subtypes that are sensitive to immunotherapy, no precise molecular subtype has
Ping Liu +5 more
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A germline pathogenic variant in BRCA2 was secondarily found through genomic sequencing of uterine serous carcinoma. Clinical response to olaparib was observed in recurrent uterine serous carcinoma with a germline BRCA2 mutation. Here, we report, for the
Kayo Inoue +4 more
doaj +1 more source

