Results 51 to 60 of about 56,601 (164)

Progesterone reduces cell survival in primary cultures of endometrioid ovarian cancer

Journal of Ovarian Research, 2019
Background Ovarian cancer is the most lethal of all gynecologic malignancies. The relationship between sexual steroids receptors and ovarian cancer progression has been largely evaluated. The presence of progesterone receptors has been associated with an
Enrique Pedernera, María J. Gómora, Flavia Morales-Vásquez, Delia Pérez-Montiel, Carmen Mendez   +4 more
doaj   +1 more source

Identification of a therapeutic target using molecular sequencing for treatment of recurrent uterine serous adenocarcinoma

Gynecologic Oncology Reports, 2019
Uterine serous adenocarcinoma is a rare but highly malignant form of endometrial cancer, comprising over 50% of recurrences and deaths from endometrial cancer.
Kelsey Musselman, Shannon Glynn, Juan Miguel Mosquera, Olivier Elemento, Andrea Sboner, Himisha Beltran, Kevin Holcomb   +6 more
doaj   +1 more source

Screening and Prevention for High-Grade Serous Carcinoma of the Ovary Based on Carcinogenesis—Fallopian Tube- and Ovarian-Derived Tumors and Incessant Retrograde Bleeding

Diagnostics, 2020
High-grade serous carcinoma (HGSC) is the most common and lethal subtype of ovarian carcinoma. Many HGSCs are now believed to originate in the fallopian tube epithelium; ovarian surface epithelium is another possible origin.
Isao Otsuka, Takuto Matsuura
doaj   +1 more source

High-grade serous ovarian carcinoma with mucinous differentiation: report of a rare and unique case suggesting transition from the “SET” feature of high-grade serous carcinoma to the “STEM” feature

Diagnostic Pathology, 2019
Background High-grade serous carcinoma, a representative high-grade ovarian carcinoma, is believed to be closely associated with a TP53 mutation. Recently, this category of ovarian carcinoma has gained increasing attention owing to the recognition of ...
Yuichiro Hatano, Maho Tamada, Nami Asano, Yoh Hayasaki, Hiroyuki Tomita, Ken-ichirou Morishige, Akira Hara   +6 more
doaj   +1 more source

MAL2 and tumor protein D52 (TPD52) are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome

BMC Cancer, 2010
Background The four-transmembrane MAL2 protein is frequently overexpressed in breast carcinoma, and MAL2 overexpression is associated with gain of the corresponding locus at chromosome 8q24.12.
Fanayan Susan, Scurry James P, Murali Rajmohan, Gloss Brian S, Hardy Jayne R, Maleki Sanaz, Byrne Jennifer A, Emmanuel Catherine, Hacker Neville F, Sutherland Robert L, deFazio Anna, O'Brien Philippa M   +11 more
doaj   +1 more source

Serous versus high-grade endometrioid endometrial carcinoma: immunohistochemistry of RFP is not useful for differentiation

Polish Journal of Pathology, 2016
We evaluated the immunohistochemical expression of ret finger protein (RFP) along with conventional immunohistochemical markers in endometrioid and serous carcinomas of the endometrium.
Cigdem Ussakli, Alp Usubutun, Nazmiye Dincer, Anil Dolgun, Diilek Bülbül, Zuhal Isikdogan, Nihan Haberal, Ozlem Ozen, Gaye Guler Tezel   +8 more
doaj   +1 more source

Serous carcinoma of endometrium in combination with neuroendocrine small-cell: A case report and literature review

Gynecologic Oncology Reports, 2016
Endometrial serous carcinomas are very clinically aggressive, which constitutes 40% of all deaths and recurrences associated with endometrial cancer.
Lorna A. Brudie, Faizan Khan, Michael J. Radi, Sarfraz Ahmad   +3 more
doaj   +1 more source

Carcinoma de ovário seroso e não seroso: tipo histológico em relação ao grau de diferenciação e prognóstico Serous and non-serous ovarian carcinoma: histological tumor type as related to the grade of differentiation and disease prognosis

Revista Brasileira de Ginecologia e Obstetrícia, 2012
OBJETIVO: Comparar as características clinicopatológicas de mulheres com carcinoma seroso e não seroso de ovário e identificar os fatores associados à sobrevida.
Patrícia Andréia Rodrigues Ferreira, Luis Felipe Trincas Assad Sallum, Luis Otávio Sarian, Liliana A. Lucci De Angelo Andrade, Sophie Derchain   +4 more
doaj   +1 more source

Expression and clinical significance of PTK7 in ovarian serous tumors

Zhongguo aizheng zazhi, 2014
Background and purpose: The protein tyrosine kinase-7 (PTK7) gene may be related to the occurrence and progression of many tumors. This study was aimed to explore the expression of PTK7 in ovarian serous tumors and its relationship with clinical stage ...
王海燕, 印永祥, 郭庆, 韦玮, 文娟娟, 彭李博, 马恒辉, 石群立, 时姗姗, 王建东   +9 more
doaj  

A retrospective study evaluating the effect of trastuzumab addition to carboplatin/paclitaxel on overall survival in patients with advanced-stage HER2/neu-overexpressing uterine serous carcinoma or carcinosarcoma

BMC Medicine
Background Uterine serous carcinoma and carcinosarcoma are aggressive forms of endometrial cancer with poor survival outcomes. Trastuzumab, a human epidermal growth factor receptor-2 (HER2)-directed monoclonal antibody, has demonstrated tumoricidal ...
Ting-Fang Lu, Lou Sun, Yu-Hsiang Shih, Yen-Fu Chen, Chun-Ting Fan, Shao-Jing Wang, Shih-Tien Hsu, Chih-Ku Liu, Sheau-Feng Hwang, Chien-Hsing Lu   +9 more
doaj   +1 more source