Results 141 to 150 of about 2,149,829 (345)

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Assessing the Diagnostic Value of VEGF Levels in Differentiation of Malignant Serous Discharge (Positive Cytology) from Benign Serous Discharge (Negative Cytology) Using ELISA Method

open access: yesمجله دانشکده پزشکی اصفهان, 2012
Background: One of the factors effective on tumor cell growth and proliferation is vascular endothelial cell growth factor (VEGF). It also affects the formation of serous fluids such as ascites or pleural effusion through vascular permeability.
Noushin Afshar Moghaddam   +2 more
doaj  

Acute Posterior Multifocal Placoid Pigment Epitheliopathy Sharing Characteristic OCT Findings of Vogt-Koyanagi-Harada Disease

open access: yesCase Reports in Ophthalmological Medicine, 2019
A 17-year-old male presented with acute bilateral paracentral scotomata and blurred vision. Funduscopic examination showed bilateral macular serous retinal detachment and yellow-white placoid lesions at the level of retinal pigment epithelium.
Yuta Kitamura   +4 more
doaj   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

open access: yesFEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

Micropulse laser for persistent optic disc pit maculopathy. A case report

open access: yesAmerican Journal of Ophthalmology Case Reports, 2018
Purpose: Optic disc pits (ODP) are rare and congenital anomalies of the optic disc, sometimes remaining asymptomatic. However, serous macular detachment or optic disc maculopathy is the most common complication, causing significant visual deterioration ...
Carlos Andrés Valdés-Lara   +4 more
doaj  

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Brolucizumab Monotherapy in Idiopathic Polypoidal Choroidal Vasculopathy:A Case Report

open access: yesRGUHS Journal of Medical Sciences
Brolucizumab a humanized single-chain antibody fragment targeting VEGF-A is approved for neovascular age-related macular degeneration nAMD and is being studied for other retinal conditions including polypoidal choroidal vasculopathy ...
Mohan S   +3 more
doaj   +1 more source

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