Results 81 to 90 of about 2,210,951 (366)

Levonorgestrel as a Potential Trigger of Acute Bilateral Central Serous Chorioretinopathy: Case Report

open access: yesCase Reports in Ophthalmology, 2023
This is a first ever report describing a case of acute bilateral central serous chorioretinopathy which developed shortly after the consumption of levonorgestrel as emergency contraception. A 27-year-old female patient visited the emergency department of
Vedran Nemet
doaj   +1 more source

Do gadolinium-based contrast agents alter 23Na T1 relaxivity in glioma? [PDF]

open access: yes, 2017
Incomplete fluid suppression on fluid-attenuated inversion-recovery 23Na-MRI (IR-23Na-MRI) was observed in three patients undergoing IR-23Na-MRI after gadolinium contrast injection, as part of a brain tumour imaging study.

core   +2 more sources

The Brescia panel and The International System for Reporting Serous Fluid Cytopathology

open access: yesCancer Cytopathology, 2020
The distinction between mesothelial proliferations and metastatic adenocarcinoma in serous fluids remains a common and vexing issue. Whereas cytomorphology allows the identification of one cell type (mesothelial) over another (epithelial), this may be ...
A. Chandra
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Preoperative systemic inflammation predicts postoperative infectious complications in patients undergoing curative resection for colorectal cancer [PDF]

open access: yes, 2009
The presence of systemic inflammation before surgery, as evidenced by the glasgow prognostic score (mGPS), predicts poor long-term survival in colorectal cancer. The aim was to examine the relationship between the preoperative mGPS and the development of
CS McArdle   +29 more
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Multiple serous membrane effusion caused by primary pericardial mesothelioma

open access: yesRadiology Case Reports, 2023
Primary pericardial mesothelioma is an extremely rare cancer with a short survival prognosis. Clinical symptoms are often atypical, and most patients are diagnosed after surgery or at autopsy.
Bui The Dung, MD   +7 more
doaj   +1 more source

Central serous chorioretinopathy: A review

open access: yesClinical and Experimental Ophthalmology, 2023
Central serous chorioretinopathy (CSC) is the fourth most common non‐surgical retinopathy associated with fluid leakage. The pathogenesis is not yet completely understood, but changes in the choroid, sclera and RPE have been described associated with ...
A. Fung, Yi Yang, A. Kam
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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