Results 91 to 100 of about 286,642 (234)

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

Advanced Science, Volume 13, Issue 52, 18 September 2026.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu, Tonghe Yang, Yuan Geng, Huan Wu, Yangrui Huang, Te Zheng, Haodi Chen, Shurui Huang, Yi Cao, Jian Yang, Wentao Yan, Yikui Zhang, Wencan Wu   +12 more
wiley   +1 more source

Fundus Autofluorescence in Acute and Chronic Central Serous Chorioretinopathy

Türk Oftalmoloji Dergisi, 2013
Pur po se: To evaluate the findings of fundus autofluorescence (FAF) imaging in acute and chronic central serous chorioretinopathy (CSC) patients.
Muhammet Kazım Erol, Özdemir Özdemir, Deniz Turgut Çoban   +2 more
doaj   +1 more source

Sporadic Retinal Astrocytic Hamartoma Mimicking Retinoblastoma in a Child: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Retinal astrocytichamartoma (RAH) is a rare benign glial neoplasm most commonly associated with tuberous sclerosis complex (TSC). Sporadic cases, occurring in the absence of systemic phakomatosis, are uncommon and may closely mimic retinoblastoma, particularly when presenting with a calcified intraocular mass, creating a diagnostic challenge ...
Mesfin Wubishet Gurmu, Samuel Negash, Aneso Mohammed, Hailu Alemu, Diriba Fufa Hordofa, Melese Abere, Lensa Million, Esubalew Mezgebu   +7 more
wiley   +1 more source

Current Therapeutic Approaches to Chronic Central Serous Chorioretinopathy

Türk Oftalmoloji Dergisi, 2019
Central serous chorioretinopathy (CSCR) is the second most common maculopathy after diabetic maculopathy between the third and fifth decades of life. CSCR is characterized by serous neurosensory retinal detachment occasionally coexisting with retinal ...
Samet Gülkaş, Özlem Şahin
doaj   +1 more source

RETINAL DISPLACEMENT AFTER RETINECTOMY IN COMPLEX MACULA-INVOLVING RECURRENT RHEGMATOGENOUS RETINAL DETACHMENT

Retinectomy, essential for treating complex rhegmatogenous retinal detachment, significantly risks retinal displacement, detectable through fundus autofluorescence.
Shaheen, Abdulla, Ghalibafan, Seyyedehfatemeh, Grau, Maria Magraner, Yannuzzi, Nicolas A., Sridhar, Jayanth, Leal, Sebastian, Rohowetz, Landon J., Cai, Louis Z.   +7 more
core   +1 more source

Cascade‐targeted intervention of the NLRP3 inflammasome and downstream angiogenesis by curcumin nanoparticles for ocular neovascularization therapy

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Ultrasound‐microreactor synthesizes monodisperse 125 nm Cur‐NPs with enhanced solubility. Cur‐NPs suppress VEGF signaling and retinal neovascularization via the NLRP3 axis. Multi‐omics profiling reveals that Cur‐NPs reprogram retinal microglia and metabolic pathways.
Siyu Jiang, Ziwei Cheng, Yujuan Cai, Yanji Zhu, Nyamjargal Nyambayar, Ruijie Lin, Li Zhang, Jian Chen, Bing Xie, Xiuping Chen   +9 more
wiley   +1 more source

Shallow Anterior Chamber in a Severe Case of Unilateral Acute Central Serous Retinal Detachment

Case Reports in Ophthalmology, 2017
Background: Atypical serous chorioretinopathy can present with symptoms similar to those of other pachychoroid diseases; however, a proper differential diagnosis will prevent unnecessary intensive treatments.
Ahmet Colakoglu, Banu Cosar
doaj   +1 more source

Case Report :Serous Retinal Detachment Following Bleb Needling

Transconjunctival bleb needling is a relatively simple and effective procedure used to restore aqueous humor outflow in failing trabeculectomy blebs. Although generally considered safe, several complications have been reported, including bleb leakage ...
Ohoud Owaidhah, Abdullah Alkandari, Sami AlShahwan, Mohammed Alsaedi, Abdullah AlZahrani   +4 more
core   +1 more source

Construction and Validation of a Long‐Term Visual Prognosis Prediction Model for Proliferative Diabetic Retinopathy After Vitrectomy Based on Machine Learning

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
This study developed and validated a machine learning‐based prognostic model for predicting long‐term visual outcomes after pars plana vitrectomy (PPV) in patients with proliferative diabetic retinopathy. ABSTRACT Introduction This study aims to develop a machine‐learning‐based risk prediction model for a long‐term visual prognosis in patients with ...
Xiaolu Wang, Jinghua Shi, Yan Gao, Tiantian Li, Xuehong Han, Lixia Guo, Tingting Jia, Yan Wang   +7 more
wiley   +1 more source