Results 101 to 110 of about 286,642 (234)
Retinal findings in membranoproliferative glomerulonephritis
Purpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations: Three women and one man were followed
Ahmad M. Mansour +6 more
doaj +1 more source
Unveiling the Functional Role of KIF21B in Microglia Inflammatory Response
Microglia express KIF21B in both sexes. KIF21B binds to microglia cytoskeleton; inflammation alters such interaction promoting a phagocytic state in females. In male microglia KIF21B modulates migration. ABSTRACT Microglia are brain immune cells that maintain homeostasis and respond to injury, changing cell morphology to drive inflammation, migration ...
Danny Ganchala +6 more
wiley +1 more source
Exudative retinal detachment refers to the separation of the neurosensory retina from the underlying retinal pigment epithelium (RPE) as a result of abnormalities of the normal hydrostatic/osmotic pressure gradients or transport mechanisms that maintain ...
Harry W. Flynn +5 more
core +1 more source
Bile acid metabolism and signaling in human and animal health: A One Health perspective
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li +7 more
wiley +1 more source
Using micro computed tomography, light microscopy and transmission electron microscopy, this study reveals that the conjunctival portions of the corneal epithelial and spectacular endothelial lining in the eye of the short‐nosed sea snake Aipysurus apraefrontalis possess high densities of microvilli to increase the surface area and two types of ...
H. Barry Collin +4 more
wiley +1 more source
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li +4 more
wiley +1 more source
Advances in FGF/FGFR Signaling: Implications for Disease and Therapy
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song +4 more
wiley +1 more source
Fabio MazzolaniPrivate Practice, Milan, ItalyBackground: The purpose of this open-label study was to investigate the effect of a curcumin-phospholipid (lecithin, Meriva®) formulation (Norflo® tablet) on visual acuity and retinal thickness
Mazzolani F
doaj
Vogt‐Koyanagi‐Harada disease in pregnancy: Case report and review of 32 patients in the literature
Key Clinical Message Systemic prednisolone including steroid pulse therapy would be safe in 32 pregnant women, who developed Vogt‐Koyanagi‐Harada disease in the literature.
Toshihiko Matsuo +2 more
doaj +1 more source
Abstract Purpose Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but may cause immune‐related adverse events (irAEs), including dry eye disease (DED). This study aimed to quantify the incidence of ICI‐associated DED and to evaluate factors contributing to variability across studies.
Kai‐Yang Chen +2 more
wiley +1 more source

