Detección de los genotipos del inhibidor de proteasa (PI) S y Z en el gen de Serpina 1 en pacientes con enfermedad pulmonar obstructiva crónica : atendidos en la sección de Neumología del Hospital Dr. Arnulfo Arias Madrid mediante la técnica PCR tiempo real en el período de 1 de octubre de 2022 al 30 de septiembre de 2023 [PDF]
La Alfa-1-Antitripsina (AAT) es una proteína, cuya función principal es inhibir las proteasas, especialmente, la Tripsina. La deficiencia de Alfa-1-Antitripsina es un desorden genético común, asociado con la retención de la proteína Alfa-1- Antitripsina
De Gracia, Lydier
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Atualização do Protocolo de Investigação de Colestase Neonatal [PDF]
, 2023 A colestase neonatal (CN) inicia-se nos primeiros três meses de vida englobando grupos de doenças extra-hepáticas e intra-hepáticas que muitas vezes apresentam altas taxas de morbimortalidade se não forem identificadas e tratadas rapidamente.
Jacinto, Joana Maria Janela
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Genomic Dysregulation by Overexpression of Transcription Factors [PDF]
, 2019 As one of the major organs, the liver plays vital roles in the homeostasis of an individual. Being able to identify master regulator genes, genes whose product can affect the activation or deactivation of other genes, will enrich our understanding of ...
Scroggins, MacKenzie
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Papel de los factores genéticos y el hábito tabáquico en el desarrollo de la enfermedad pulmonar obstructiva crónica (EPOC) [PDF]
, 2018 Introducción La EPOC es definida como una enfermedad del sistema respiratorio en la que se produce una limitación crónica y progresiva al flujo aéreo. Sus principales síntomas son disnea, tos crónica y expectoración.
Francés Pardo, Sara
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Nedostatak alfa-1 antitripsina kod dece - kliničke odlike i dijagnostika [PDF]
, 2014 Introduction Alpha-1-antitrypsin deficiency (AATD) is a relatively rare and clinically very heterogeneous autosomal recessive disorder. Objective Presentation of clinical characteristics of AATD in the first months after birth, as well as the ...
Baletić, Anđelo +7 more
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Primate proteomic composition of seminal plasma and prostate-specific transglutaminase activity in relation to sexual selection. [PDF]
, 2017 Humans (Homo sapiens), chimpanzees (Pan troglodytes), and gorillas (Gorilla gorilla) have diverse mating systems with varying levels of sperm competition. Several seminal plasma genes have been claimed to evolve under positive selection, while others are
Zielen, Amanda M.C.
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Differential Macrophage Polarization Promotes Tissue Remodeling and Repair in a Model of Ischemic Retinopathy [PDF]
Diabetic retinopathy is the leading cause of visual loss in individuals under the age of 55. Umbilical cord blood (UCB)–derived myeloid progenitor cells have been shown to decrease neuronal damage associated with ischemia in the central nervous system ...
A Fantin +48 more
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Efeitos da angiotensina II na regulação do sistema plasminogênio-plasmina em células endometriais estromais humanas : possível papel na patogenia da endometriose [PDF]
, 2022 Introdução. A endometriose é caracterizada pela presença de tecido estromal endometrial fora da cavidade uterina. As células do estroma endometrial humano (hESCs) têm um papel essencial na endometriose, uma vez que essas células podem adquirir um perfil ...
Zanon, Pamela
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Prostate cancer exosomes differentiate BM-MSCs into pro-angiogenic and pro-Invasive myofibroblasts [PDF]
The reactive stroma in prostate cancer is predominantly composed of myofibroblasts, which are thought to be required for tumour progression. Bone-marrow derived mesenchymal stem cells (BM-MSCs) are known to migrate into the tumour and are one of the many
Chowdhury, Ridwana
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