Results 41 to 50 of about 667 (110)

Urinary proteomics reveals biological processes related to acute kidney injury in Bothrops atrox envenomings.

PLoS Neglected Tropical Diseases
Acute kidney injury (AKI) is a critical systemic complication caused by Bothrops envenoming, a neglected health problem in the Brazilian Amazon. Understanding the underlying mechanisms leading to AKI is crucial for effectively mitigating the burden of ...
Lisele Maria Brasileiro-Martins, Sofia Angiole Cavalcante, Thaís Pinto Nascimento, Alexandre Vilhena Silva-Neto, Marlon Dias Mariano Santos, Amanda C Camillo-Andrade, Juliana de Saldanha da Gama Fischer, Caroline Coelho Ferreira, Lucas Barbosa Oliveira, Marco Aurelio Sartim, Allyson Guimarães Costa, Manuela B Pucca, Fan Hui Wen, Ana Maria Moura-da-Silva, Jacqueline Sachett, Paulo Costa Carvalho, Priscila Ferreira de Aquino, Wuelton M Monteiro   +17 more
doaj   +1 more source

Impact of Gene Modifiers on Cystic Fibrosis Phenotypic Profiles: A Systematic Review

Human Mutation, Volume 2024, Issue 1, 2024.
Cystic fibrosis (CF) is a complex monogenic disorder with a large variability in disease severity. Growing evidence suggests that the variation observed depends not only on variations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene but also on modifier genes.
Anastasia Ward, Ramil Mauleon, Chee Y. Ooi, Nedeljka Rosic, George P. Patrinos   +4 more
wiley   +1 more source

Zapalenie tkanki podskórnej jako rzadki objaw kliniczny genetycznie uwarunkowanych zaburzeń α1-antytrypsyny – przegląd piśmiennictwa

Przegląd Dermatologiczny, 2011
α1-Antitrypsin (AAT) is a serine protease inhibitor responsible forregulating proteinases' activity in the blood. α1-Antitrypsin deficiencyis a result of SERPINA 1 gene mutation and it is one of the most commongenetic abnormalities in Caucasians.
Agata Maciejewska-Radomska, Aleksandra Wilkowska   +1 more
doaj  

Construction and Validation of a Risk Prediction Model for Colon Adenocarcinoma Prognosis Based on 11 Depression‐Related Genes

International Journal of Genomics, Volume 2024, Issue 1, 2024.
Background: The influences of depression on cancer have noticeably attracted scholars’ attention. This study is aimed at exploring the relationships between depression and colon adenocarcinoma (COAD). Methods: Differentially expressed genes in COAD were overlapped with depression‐related genes (DRGs) to obtain COAD‐DRGs. A risk model was constructed to
Yunchuan Yuan, Lili Xia, Xintong Wu, Hongjing Yang, Lu Dou, Zhengrui Li   +5 more
wiley   +1 more source

PO:36:250 | Eosinophilic granulomatosis with polyangiitis associated to Alpha-1 Antitrypsin Deficiency: a land still unexplored

Reumatismo
Background. Eosinophilic Granulomatosis with Polyangiitis (EGPA) is a small-vessel vasculitis often associated with ANCA auto-antibodies. Alpha-1 Antitrypsin Deficiency (AATD) is an autosomal hereditary condition involving mainly lungs and liver, caused ...
Società Italiana di Reumatologia
doaj   +1 more source

MTHFR (C677T E A1298C) E SERPINA-1 (G43A) EM PUÉRPERAS COM HISTÓRICO DE PARTO PREMATURO E PERDA FETAL

Hematology, Transfusion and Cell Therapy, 2022
EJS Freitas, RS Brito, JPM Neto
openaire   +1 more source

Partial Thyroid Hormone-Binding Globulin Deficiency: A Case Report and Literature Review. [PDF]

Diabetes Metab Syndr Obes, 2023
Liu X, Li S, Xiong J, Chen D, Jiang C, Zeng L, Qiu Y, Xia BW.   +7 more
europepmc   +1 more source

Proteomic profiling of urine identifies specific fragments of SERPINA1 and albumin as biomarkers of preeclampsia. [PDF]

Am J Obstet Gynecol, 2008
Buhimschi IA, Zhao G, Funai EF, Harris N, Sasson IE, Bernstein IM, Saade GR, Buhimschi CS.   +7 more
europepmc   +1 more source

Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice. [PDF]

Proc Natl Acad Sci U S A, 2021
Deuse T, Tediashvili G, Hu X, Gravina A, Tamenang A, Wang D, Connolly A, Mueller C, Mallavia B, Looney MR, Alawi M, Lanier LL, Schrepfer S.   +12 more
europepmc   +1 more source

Loss of Serpina1 in Mice Leads to Altered Gene Expression in Inflammatory and Metabolic Pathways. [PDF]

Int J Mol Sci, 2022
Meghadri SH, Martinez-Delgado B, Ostermann L, Gomez-Mariano G, Perez-Luz S, Tumpara S, Wrenger S, DeLuca DS, Maus UA, Welte T, Janciauskiene S.   +10 more
europepmc   +1 more source