Results 301 to 310 of about 1,288,749 (348)

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

Advanced Science, EarlyView.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu, Wanyi Zhao, Xinyu Chen, Yanzhou Wang, Shuoshuo Wei, Bo Xiang, Yingzhou Shi, Zongyue Li, Yangyang Yao, Jin Xie, Renyuan Qiu, Meng Shu, Shuo Xu, Ping Chen, Zhiying Chen, Yingjie Wu, Weibo Xia, Ling Gao, Yongfeng Song, Jiajun Zhao, Chao Xu   +20 more
wiley   +1 more source

Theoretical and experimental study into laser-induced gold nanoparticles for superior surface-enhanced raman spectroscopy applications. [PDF]

Sci Rep
Javanmard N, Sovizi M, Aliannezhadi M.
europepmc   +1 more source

Single-Molecule SERS Discrimination of Proline from Hydroxyproline Assisted by a Deep Learning Model

Yingqi Zhao, Kang Zhan, Pei-Lin Xin, Zaoping Chen, Shuai Li, Francesco De Angelis, Jian‐An Huang   +6 more
openalex   +1 more source

Non‐Monotonic Ion Conductivity in Lithium‐Aluminum‐Chloride Glass Solid‐State Electrolytes Explained by Cascading Hopping

Advanced Science, EarlyView.
Cascading hopping events of lithium ions are identified as the main ion conduction mechanism in inorganic glass solid‐state electrolytes. Machine learning molecular dynamics simulations and hop function analysis confirm that pairs of lithium ions carry out cascading hopping motions.
Beomgyu Kang, Jina Yu, Shinji Saito, Jihyun Jang, Bong June Sung   +4 more
wiley   +1 more source

Rapid and sensitive acute leukemia classification and diagnosis platform using deep learning-assisted SERS detection. [PDF]

Cell Rep Med
Zhang D, Cheng Z, Song Y, Li H, Shi L, Wang N, Peng Y, Chen R, Sun N, Han M, Hu F, Zong C, Zhang R, Chen S, Zhu C, Zhang X, Li X, Ma X, Shi C, Zhang X, Liu R, Ren Z, Wang L, Zeng Q, Zeng T, Chen X.   +25 more
europepmc   +1 more source

ERβ/circAHNAK Axis Inhibits USP10–FMR1 Deubiquitination to Prevent m⁶A‐Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In clear cell renal cell carcinoma, estrogen receptor β (ERβ) upregulates circAHNAK, which competitively binds USP10 to prevent FMR1 deubiquitination, leading to FMR1 degradation. Loss of FMR1 hinders m⁶A‐dependent decay of ADAM17 mRNA, resulting in ADAM17 accumulation in tumor exosomes and enhanced angiogenesis.
Chao Xu, Sujing Zhang, Yuepeng Liu, Jingwei Lv, Yilong Cao, Yao Chen, Hao Sun, Bowei Zhang, Shengtao Dai, Jiehan Li, Xiaoling Li, Bei Shi, Qingyun Sun, Meng Zhu, Junfei Gu   +14 more
wiley   +1 more source

SERS Response of Graphene Oxide on Magnetron-Sputtered Gold Films. [PDF]

Nanomaterials (Basel)
Politano GG.
europepmc   +1 more source

Identification of a Pair of Linear or Cyclic Naturally Inspired Bifunctional Lipopeptide Antibiotics That Overcome Antimicrobial Resistance

Advanced Science, EarlyView.
The underexplored bacterial genus Aquimarina harbors a large biosynthetic potential for discovering new antibiotics. Here, the authors identify a pair of linear or cyclic bifunctional cationic lipopeptide antibiotics, aquicidine L and C4, inspired by the aquicidine gene cluster from Aquimarina.
Lei Li, Yiwen Zhou, Yuzhu Wu
wiley   +1 more source

Disposable Copper Electrodes Based on Printed Circuit Board Technology for the <i>Operando</i> Generation of Raman-Enhancing Substrates. [PDF]

Anal Chem
Perez-Estebanez M, Romay L, Huidobro M, Nuñez-Marinero P, Heras A, Del Campo FJ, Colina A.   +6 more
europepmc   +1 more source

RiboMicrobe: An Integrated Translatome Atlas for Microorganism

Advanced Science, EarlyView.
RiboMicrobe is a comprehensive database for Ribo‐seq data from prokaryotes, featuring 891 Ribo‐seq, 369 RNA‐seq, and 62 proteome datasets from 38 species. The database not only provides various data visualization results but also includes two sORF prediction models and a suit of bioinformatics tools for comparative analysis, facilitating easy access ...
Yingshun Zhou, Jinjing Luo, Xiaoqiang Lang, Yuli Gan, Guoxian Liu, Yuling Cui, Fazhi Li, Weicong Zhu, Bing Chen, Yuanyuan Dong, Yinglin Wu, Yi Cao, Qi Liu   +12 more
wiley   +1 more source