Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Application of Agroforestry By-product Based Nanocellulose in Food Industry
Shipin gongye ke-ji, 2023 Cellulose is one of the abundant natural polymers in nature, which is renewable, environmentally friendly and biocompatible. Nanocellulose is prepared by physical or chemical method from cellulose.
Jun ZENG +3 more
doaj +1 more source
SERS Detection of Graphene Oxide in Acid Catalyzed Sol-Gels [PDF]
, 2017 Silica sol-gel and aerogel substrates were synthesized using a modified acid catalyzed hydrolysis of tetramethyl orthosilicate method that incorporated graphene oxide and silver nanoparticles into the matrix.
Atkinson, Elizabeth J.O. +1 more
core +1 more source
Readout fidelity of coaxial holographic digital data page recording in nanoparticle–(thiol–ene) polymer composites [PDF]
, 2016 We report on an experimental investigation of nanoparticle-concentration and thiol-to-ene stoichiometric ratio dependences of symbol error rates (SERs) and signal-to-noise ratios (SNRs) of digital data pages recorded at a wavelength of 532 nm in thiol ...
Eiji Hata, Kohta Nagaya, Yasuo Tomita
core +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Ser indio, ser negro, ser mestizo
Chasqui, 1991 ----
Robles, Jaime, Little, Paul
openaire +2 more sources
Determination of the Optimal Conditions for Bovine Serum Albumin Surface Enhanced Raman Scattering on Silver Colloids [PDF]
, 2011 Bovine serum albumin (BSA) was analyzed using surface enhanced Raman scattering (SERS) to find the optimal conditions to observe BSA with SERS. Colloidal silver, Na2SO4, and BSA were mixed together at varying pHs and concentrations to obtain multiple ...
Gilbert, Brian, Reyes, Joell D.
core +1 more source
Boron Nitride Nanosheets Improve Sensitivity and Reusability of Surface Enhanced Raman Spectroscopy
, 2016 Surface enhanced Raman spectroscopy (SERS) is a useful multidisciplinary analytic technique. However, it is still a challenge to produce SERS substrates that are highly sensitive, reproducible, stable, reusable, and scalable.
Cai, Qiran +8 more
core +1 more source
Surface enhanced Raman spectroscopy on single mode nanophotonic-plasmonic waveguides [PDF]
, 2016 We analyze the generation of Surface Enhanced Raman Spectroscopy signals from integrated bowtie antennas, excited and collected by a single mode silicon nitride waveguide, and discuss strategies to enhance the Signal-to-Noise ...
Baets, Roel +4 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source