Results 61 to 70 of about 1,286,865 (349)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

SERS study of different species of p-aminothiophenol adsorbed on silver nanoparticles [PDF]

open access: yes, 2018
In the present work we have focused the discussion on the experimental and theoretical SERS spectra of the organic compound pATP recorded on silver colloids.
López-Ramírez, María Rosa   +3 more
core  

A review on applications of two-dimensional materials in surface enhanced Raman spectroscopy [PDF]

open access: yes, 2017
Two-dimensional (2D) materials, such as graphene and MoS2, have been attracting wide interest in surface enhancement Raman spectroscopy. This perspective gives an overview of recent developments in 2D materials' application in surface enhanced Raman ...
Xia, Ming
core   +3 more sources

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla   +15 more
wiley   +1 more source

SERS Detection of Graphene Oxide in Acid Catalyzed Sol-Gels [PDF]

open access: yes, 2017
Silica sol-gel and aerogel substrates were synthesized using a modified acid catalyzed hydrolysis of tetramethyl orthosilicate method that incorporated graphene oxide and silver nanoparticles into the matrix.
Atkinson, Elizabeth J.O.   +1 more
core   +1 more source

Theory of hyperbolic stratified nanostructures for surface enhanced Raman scattering

open access: yes, 2017
We theoretically investigate the enhancement of surface enhanced Raman spectroscopy (SERS) using hyperbolic stratified nanostructures and compare to metal nanoresonators.
Axelrod, Simon   +4 more
core   +1 more source

Review of SERS Substrates for Chemical Sensing

open access: yesNanomaterials, 2017
The SERS effect was initially discovered in the 1970s. Early research focused on understanding the phenomenon and increasing enhancement to achieve single molecule detection. From the mid-1980s to early 1990s, research started to move away from obtaining
P. Mosier-Boss
semanticscholar   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Star-Shaped Fe3-xO4-Au Core-Shell Nanoparticles: From Synthesis to SERS Application

open access: yesNanomaterials, 2020
In this work, the preparation of magneto-plasmonic granular nanostructures and their evaluation as efficient substrates for magnetically assisted surface enhanced Raman spectroscopy (SERS) sensing are discussed.
Thi Thuy Nguyen   +3 more
doaj   +1 more source

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