Results 41 to 50 of about 212 (130)

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Recurrent Gynandroblastoma with Juvenile Granulosa cell tumor, a very rare ovarian tumor in a 29-year-old patient: A case report [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Introduction: Ovarian sex cord stromal tumors present with ovarian masses and symptoms resulted from increased hormone secretion. Gynandroblastoma is a rare tumor consisting of two components: granulosa cell tumor and Sertoli or Sertoli-Leydig cell tumor.
Mehran Toqtamesh, Amir-Hossain Jafariyan, Zahra Akbari, Helena Azimi, Yasser Hasanzadeh, Hossein Bozorgi   +5 more
doaj   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Incidental detection of a virilizing Sertoli-Leydig cell tumor during cesarean section: A case report

Case Reports in Women's Health
Sertoli-Leydig cell tumors are a rare type of sex cord-stromal tumors that are mostly hormonally active (androgenic or estrogenic). Owing to the rarity of this disease, its impact on pregnancy is not fully understood.
Roza Mahyoob, Keisuke Sugita, Akiko Yamamoto   +2 more
doaj   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben, Anne Prinsen, Laetitia de Kort, Jetske van Breda   +3 more
wiley   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Sertoli-Leydig Cell -A Rare Male Hormone Producing Ovarian Tumor

Journal of Bahria University Medical and Dental College, 2013
Sertoli-Leydig cell tumor (SLCT) of ovary is an unusual neoplasm that belongs to a group of sex cord-stromal tumors of ovary. It accounts for less than 0.5% of all primary ovarian neoplasms.
Khalida Nasreen, Rozina Mustafa
doaj  

Unusual malignant neoplasms of ovary in children: two cases report [PDF]

Korean Journal of Pediatrics, 2016
Sex cord tumors with annular tubules are known to originate from the sex cord of embryonic gonads that synthesize Sertoli cells, Leydig cells, granulosa cells, and theca cells of the ovarian stroma, while ovarian small cell carcinoma of the hypercalcemic
Ali Ghribi, Aicha Bouden, Manef Gasmi, Mourad Hamzaoui   +3 more
doaj   +1 more source

SERTOLI - LEYDIG CELL TUMOR : A RARE OVARIAN TUMOR

Journal of Evolution of Medical and Dental Sciences, 2014
Sertoli- Leydig cell tumor or "Androblastoma" or "Arrhenoblastoma" is a rare virilizing tumor of ovary, mostly with masculinizing features. Many but certainly not all tumors are hormonally active. Although classified under malignant tumors the degree of malignancy is less than that of ovarian carcinoma in general.
Lavanya Kumari Sarella, Usha Sree D
openaire   +1 more source