Results 61 to 70 of about 212 (130)

Tumores testiculares na infância Testicular tumors in childhood

Acta Cirúrgica Brasileira, 2003
Trata-se de um artigo de revisão de tumores testiculares na infância que representam 1 a 2% dos tumores sólidos pediátricos. Os tumores germinativos representam 60 a 75% dos tumores testiculares pediátricos. Destes o mais comum é o tumor de saco vitelino
Adauto José Cologna, Antonio Carlos Pereira Martins, Silvio Tucci Jr, Haylton Jorge Suaid, Fábia Martins Celini, Ricardo Mesquita Paschoal, Edson Luis Paschoalin   +6 more
doaj   +1 more source

Serine Ameliorates Cadmium‐Induced Testicular Injury by Regulating the PGAM1/PHGDH Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Serine mitigates cadmium‐induced testicular injury in mice by inhibiting the PGAM1/PHGDH pathway, restoring ion homeostasis and glycolysis, and relieving oxidative stress, inflammation, fibrosis, and apoptosis. ABSTRACT Cadmium (Cd) is a widespread environmental contaminant that impairs male reproductive function; however, the metabolic mechanisms ...
Xueru Wang, Na Luo, Yonggang Ma, Hui Zou, Xishuai Tong, Jiaqiao Zhu, Ruilong Song, Hongyan Zhao, Zongping Liu   +8 more
wiley   +1 more source

Nano‐Rosmarinic Acid Protects Against Chlorfenapyr‐Induced Testicular Toxicity Through Modulation of NRF2/HO‐1 and NF‐κB/NLRP3 Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Chlorfenapyr reduces testicular weight, sperm quality, and reproductive hormones. This study highlights that RA within chitosan nanoparticles (RA‐CHNPs) are superior to Rosmarinic acid in mitigating CFP‐induced testicular damage. RA within chitosan nanoparticles leads to the reduction of NF‐κB and NLRP3 expression in seminiferous tubules and activates ...
Ahmad Najem Alshammari, Ayat B. Al‐Ghafari, Huda A. Al Doghaither, Ahmed M. S. Hegazy, Ekramy M. Elmorsy, Asmaa Fady Sharif, Zahraa Khalifa Sobh   +6 more
wiley   +1 more source

Prospective external validation of ADNEX and RMI for estimating risk of malignancy in adnexal masses in general gynecological settings: Danish multicenter study

Ultrasound in Obstetrics &Gynecology, Volume 68, Issue 2, Page 256-269, August 2026.
ABSTRACT Objectives The primary aims of this study were to validate externally the diagnostic performance of the Assessment of Different NEoplasias in the adneXa (ADNEX) model for distinguishing between malignant and benign adnexal masses, when used by non‐expert ultrasound examiners in general gynecological settings with a low prevalence of ovarian ...
I. M. Dueholm Hjorth, B. H. Bech, A. Ledger, C. Møller, T. Van den Bosch, O. Mogensen, Collaborators, R. Al Taie, C. Blach Kristensen, M. Lundegaard Iversen, P. Bor, M. Stentebjerg   +11 more
wiley   +1 more source

Menopausal hormone therapy after ovarian cancer: A 10‐year survival analysis in premenopausal women

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1468-1479, August 2026.
Among premenopausal women surgically treated for ovarian cancer, no difference in 10‐year overall survival was observed between postoperative MHT users and non‐users. Young ovarian cancer survivors should be recommended MHT after surgically induced menopause.
Åsa Ehlin von Kartaschew, Pernilla Dahm‐Kähler, Kenny Rodriguez Wallberg, Erik Holmberg, Angelique Flöter‐Rådestad   +4 more
wiley   +1 more source

Bilateral, metachronic ovarian Sertoli–Leydig cell tumour in an 11-year-old patient: A case report

Revista Médica del Hospital General de México, 2018
Sertoli–Leydig cell tumours (SLCT) are rare tumours, accounting for less than 0.5% among the ovarian tumours, and occur most frequently in the second and third decades. The majority of them are unilateral and diagnosed at stage I.
C. Gómez-Peñaloza, A. Cañavera-Constantino, G. Aristi-Urista   +2 more
doaj   +1 more source

Sertoli-Leydig cell tumor of the ovary.

Journal of the Formosan Medical Association = Taiwan yi zhi, 2004
Sertoli-Leydig cell tumors of the ovary are rare diseases that occur primarily in young women. The majority of these tumors are unilaterally localized, and conservative surgery is sufficient. However, these tumors exhibit a variety of histological patterns, which are significant prognostic factors. To date, no standard therapy exists.
Fang-Yi, Chen, Bor-Ching, Sheu, Ming-Chieh, Lin, Song-Nan, Chow, Ho-Hsiung, Lin   +4 more
openaire   +1 more source

MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy

Cancer Science, Volume 117, Issue 8, Page 2085-2097, August 2026.
MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
wiley   +1 more source

Steroid Cell Ovarian Neoplasm, Not Otherwise Specified: A Case Report and Review of the Literature

Case Reports in Obstetrics and Gynecology, 2012
Background. Steroid cell ovarian tumors, not otherwise specified, represent a unique cause of female virilization. Most commonly encountered in premenopausal women, these tumors can exist throughout a women’s lifetime, from before puberty until after ...
Paul Singh, Frank Deleon, Ralph Anderson
doaj   +1 more source

Diagnostic Dilemma in Two Cases of Hyperandrogenism

Case Reports in Endocrinology, 2018
Hirsutism is a common endocrine complaint affecting about 10 percent of women. It may be caused by multiple etiologies including adrenal and ovarian disorders. Usually, it is a result of a benign entity such as PCOs and idiopathic hirsutism.
Ibrahim Alali, Lilianne Haj Hassan, Ghadeer Mardini, Nermeen Hijazi, Lama Hadid, Younes Kabalan   +5 more
doaj   +1 more source