Results 91 to 100 of about 32,541 (263)

The sclerosing Sertoli cell tumor of the testis is an extremely rare entity [PDF]

open access: gold, 2020
Faaz Salah Gomha   +9 more
openalex   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

open access: yesAndrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda   +7 more
wiley   +1 more source

PTBP1 supports mouse spermatogenesis by facilitating cytoskeletal organization through the mTORC2–PKCα pathway in Sertoli cells

open access: yesCommunications Biology
Somatic Sertoli cells in the seminiferous tubule provide structural and paracrine support for spermatogenesis. Proper regulation of Sertoli cell cytoskeleton dynamics is essential for this function; however, the regulatory mechanisms remain unclear. Here,
Manabu Ozawa   +8 more
doaj   +1 more source

Unveiling the roles of Sertoli cells lineage differentiation in reproductive development and disorders: a review

open access: yesFrontiers in Endocrinology
In mammals, gonadal somatic cell lineage differentiation determines the development of the bipotential gonad into either the ovary or testis. Sertoli cells, the only somatic cells in the spermatogenic tubules, support spermatogenesis during gonadal ...
Yang Gao   +12 more
doaj   +1 more source

Diagnostic performance of the microRNA‐371a assay in small testicular masses: a real‐world cohort study

open access: yesBJU International, EarlyView.
Objectives To evaluate the diagnostic performance of the Conformité Européenne [CE]‐certified microRNA‐371a‐3p (miR371a) assay in patients undergoing inguinal exploration for small testicular masses of unknown histology in a real‐world setting. Patients and Methods Between March 2023 and March 2024, 60 patients underwent inguinal exploration for ...
Felix Seelemeyer   +6 more
wiley   +1 more source

Spectrum of Hypogonadism and Its Management in Adolescents With Prader‐Willi Syndrome: A Retrospective Cohort Study Over 35 Years

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Context Adult data indicate that hypogonadism is underdiagnosed and undertreated in Prader‐Willi Syndrome (PWS). Objectives We aimed to describe the spectrum of pubertal development, and the diagnosis and treatment of hypogonadism in paediatric/adolescent patients with PWS. Design/Patients A retrospective cohort study of patients with PWS aged
Helen Nguyen   +2 more
wiley   +1 more source

A Sertoli-Leydig ovarian tumor presenting as ovarian torsion: A case report

open access: yesCase Reports in Women's Health
Torsion occurs as a complication in 10% of cases of ovarian tumors. It predominantly occurs in benign ones, while malignant tumors are less prone to torsion.
Samia Tligui   +6 more
doaj   +1 more source

Mechanobiology in Stem Cell‐Based Bioprinting

open access: yesCell Proliferation, EarlyView.
Mechanobiology in stem cell‐based bioprinting is an emerging field that bridges the mechanical conditions of the bioprinting process with the regulation of stem cell behaviour for engineering living tissues. Stresses encountered during bioprinting, together with the mechanical properties of bioinks, play a critical role in regulating stem cell ...
Supeng Ding, Tiankun Liu, Rui Yao
wiley   +1 more source

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