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Sertoli Cell

2018
There is more than a century and a half that the polarized Sertoli cell which extends from the base of the seminiferous tubule to its lumen has been identified as being a “nurse cell” for germ cells. This Sertoli cell nursing function relies on a cytosqueleton displaying all possible properties of plasticity to adapt to the cyclicity of spermatogenesis,
Jégou, Bernard, Rolland, Antoine D.
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The Sertoli cell

General and Comparative Endocrinology, 1972
Abstract Electron-microscopic studies indicate that Sertoli cells often possess the fine structure normally associated with steroid-producing tissues. In addition, a Δ 5 -3 β -hydroxysteroid dehydrogenase reaction has been recorded in these cells throughout the vertebrate series.
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Sertoli cell testicular tumors

Urology, 1981
The testicular Sertoli cell tumor is generally considered a benign tumor that can be treated by orchiectomy and close follow-up. It accounts for less than 1.5 per cent of testis tumors and may be malignant in 10 per cent of cases. Approximately 30 per cent have endocrine activity. We present 5 additional cases to the 75 previously reported in the world
R, Littleton   +3 more
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Sertoli cell tumours in the bull

Journal of Comparative Pathology, 1976
Abstract Examination of the testes of 1598 bulls slaughtered at abattoirs in north Queensland revealed the presence of Sertoli cell tumours in one mature and five aged bulls. Tumours were present as discrete pale nodules, 1·0 to 3·0 cm. in diameter. They were characterized histologically by a distinct tubular pattern, variable intertubular fibrosis,
P W, Ladds, P J, Saunders
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Intermediate filaments in sertoli cells

Microscopy Research and Technique, 1992
AbstractUsing immunohistochemical techniques both at light and electron microscopic levels, the arrangement and distribution of intermediate filaments in Sertoli cells of normal testis (in rat and human), during pre‐ and postnatal development (in rabbit, rat, and mouse) and under experimental and pathological conditions (human, rat), have been studied ...
G, Aumüller, C, Schulze, C, Viebahn
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Three‐dimensional reconstruction of a rat stage V Sertoli cell: II. Morphometry of Sertoli–Sertoli and Sertoli–germ‐cell relationships

American Journal of Anatomy, 1983
AbstractSertoli–Sertoli and Sertoli–germ‐cell configurational relationships were studied using morphometric techniques and direct measurements as obtained from micrographs used to reconstruct a model of a rat stage V Sertoli cell. Regional areas of the Sertoli cell surface, which faced germ cells, other Sertoli cells, or noncellular structures, were ...
J E, Weber   +3 more
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[The Sertoli cell].

Morphologie : bulletin de l'Association des anatomistes, 2012
The Sertoli cell is essential for the formation and functioning of the testis. This is the first cell to differentiate into the initially bipotential genital ridge and is the only somatic cell present in seminiferous tubules. Maturation involves the loss of proliferative capacity, formation of intercellular tight junctions and the appearance of some ...
C, Ravel, S, Jaillard
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Relaxin and Sertoli cell proliferation

Italian Journal of Anatomy and Embryology, 2014
Immature Sertoli cells proliferate and several factors affect their number, including the follicle stimulating hormone (FSH), testosterone, estradiol and several paracrine growth factors. Using a primary culture of Sertoli cells isolated from 15-day old Wistar rats we have shown that relaxin stimulates Sertoli cell proliferation through the activation ...
Nascimento, Aline R.   +4 more
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Hormone interactions in the sertoli cells

In Vitro, 1979
The effects of follicle-stimulating hormone (FSH) and testosterone in rat Sertoli cells were investigated in vitro by means of isolated cell populations. The Sertoli cells selectively bind FSH, and respond to FSH stimulation with increased accumulation of endogenous cyclic AMP and secretion of androgen-binding protein (ABP).
A, Steinberger   +5 more
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Sertoli-Leydig cell tumor

Archives of Gynecology and Obstetrics, 2001
Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl.
T, Lantzsch   +5 more
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