Results 141 to 150 of about 1,897,479 (242)

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Evaluation of Human Serum Albumin Nanoparticles for Rapamycin Delivery. [PDF]

ACS Omega
Rodero CF, Pangua C, Gracia JM, Suner MB, Guiguer MT, Chorilli M, Irache JM.   +6 more
europepmc   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

Advanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn, Marie Baiker, Yajuan Jiang, Ebru Aksoy, Kurt Pfannkuche, Horst Fischer   +5 more
wiley   +1 more source

Multi‐Parametric Fluorescence Spectroscopy for the Detection and Characterization of Plant‐Derived Protein Residues on 316L Stainless Steel

Advanced Materials Interfaces, EarlyView.
UV–vis fluorescence spectroscopy enables sensitive monitoring of plant protein adsorption on AISI 316L stainless steel under food‐processing‐relevant conditions. Spectral deconvolution reveals adsorption‐induced changes associated with protein–surface interactions and conformational alterations, demonstrating the potential of the technique for ...
Alexander Khort, Erik Jansson, Gunilla Herting, Eva Blomberg, Kirsti Viljaste, Ahana Mukherjee, Inger Odnevall   +6 more
wiley   +1 more source

Formation and Characterization of Nanoparticles from Avocado Peel Extract and Bovine Serum Albumin. [PDF]

Molecules
Sánchez-Segura L, Zavala-García LE, Vázquez-Martínez J, Martínez-Gutiérrez E.   +3 more
europepmc   +1 more source

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

Advanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti, M. Ballerini, A. Mantegazza, P. Occhetta, M. Rasponi   +4 more
wiley   +1 more source

The Role of Serum Albumin as a Prognostic Marker in Guillain-Barré Syndrome: A Systematic Review. [PDF]

J Inflamm Res
Puspitasari V, Arjuna YYE, Purnomo AE, Siahaan YMT.   +3 more
europepmc   +1 more source

Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications

Advanced Materials Technologies, EarlyView.
This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo, Sina Jamali, Nam‐Trung Nguyen   +2 more
wiley   +1 more source

Nitrogen-Drag-Assisted Crosslinking by Glucose to Obtain Bovine Serum Albumin-SGI-1027 Nanoparticles. [PDF]

Pharmaceutics
López MG, Zavala-García LE, Kú-González ÁF, Solís-Hernández A, Carriles R, Zaina S, Sánchez-Segura L.   +6 more
europepmc   +1 more source

Silk Fibroin Nanofiber–Immobilized Horseradish Peroxidase Enables Continuous Preparation of Injectable Hydrogels With Negligible Residual Enzyme for Drug Delivery

Advanced Materials Technologies, EarlyView.
Overcoming the immunogenicity challenges of enzyme‐mediated crosslinking, a flow‐through reactor utilizing SFNF‐HRP enables the continuous production of injectable hydrogels. This continuous platform ensures homogeneous crosslinking while minimizing residual HRP in the resulting hydrogels.
Ayari Miyawaki, Shinji Sakai
wiley   +1 more source