Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease [PDF]
Nature Medicine, 2019 Neurofilament light chain (NfL) is a promising fluid biomarker of disease progression for various cerebral proteopathies. Here we leverage the unique characteristics of the Dominantly Inherited Alzheimer Network and ultrasensitive immunoassay technology ...
Stephanie A Schultz +2 more
exaly +3 more sources
Epigallocatechin-3-Gallate: A potential amyloid Fibril Disaggregator of Serum amyloid A1 [PDF]
Biochemistry and Biophysics ReportsSerum amyloid A1 (SAA1) is a 122-amino acid protein that, after cleavage, matures into a 104-amino acid form. Its N-terminus is responsible for binding high-density lipoprotein (HDL), while the C-terminus maintains its structural integrity.
Natalie G. Horgan +8 more
doaj +2 more sources
Serum Amyloid A Concentrations in Young Japanese Black Cattle: Relationship with Colostrum Intake and Establishing Cut-Off Concentrations [PDF]
AnimalsThis study aimed to investigate the variations in serum amyloid A (SAA) concentrations and influencing factors in young Japanese Black (JB) cattle. The cut-off values were 18.5 mg/L, 17.7 mg/L, 14.4 mg/L, and 8.1 mg/L at 30–59, 60–89, 90–119, and 120–300
Urara Shinya +7 more
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The role of Xuanfei Zhisou mixture plus fluticasone propionate suspension in the treatment of variant cough in children and its effect on serum amyloid A and c-reactive protein. [PDF]
Front Med (Lausanne)Zhang Y, Song Y, Xue J, Xue N.
europepmc +3 more sources
ALX/FPR2 Contributes to Serum Amyloid A-Induced Lung Neutrophil Recruitment Following Acute Ozone Exposure. [PDF]
FASEB JYaeger MJ +16 more
europepmc +3 more sources
Evaluation of serum amyloid a and procalcitonin in some inflammatory diseases of cattle [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2020 Recent study in humans and animal has been focused on inflammatory biomarkers that infectious diseases, such as serum amyloid A (SAA), procalcitonin (PCT), that may more accurately and efficiently diagnose inflammation.
Onur BASBUG +2 more
doaj +1 more source
Maternal Serum Amyloid A as a Marker of Preterm Birth/PROM: A Systematic Review and Meta-Analysis
Medicina, 2023 Background and Objectives: Preterm birth, one of the leading causes of neonatal mortality, occurs in between 5 and 18% of births. Premature birth can be induced by a variety of triggers, including infection or inflammation.
Ioana-Evelina Chiriac +7 more
doaj +1 more source
SARS-CoV-2-Induced Amyloidgenesis: Not One, but Three Hypotheses for Cerebral COVID-19 Outcomes
Metabolites, 2022 The main neuropathological feature of Alzheimer’s disease (AD) is extracellular amyloid deposition in senile plaques, resulting from an imbalance between the production and clearance of amyloid beta peptides.
Carlos-Alberto Gonçalves +3 more
doaj +1 more source
Serum amyloid A levels in acute and chronic urticaria [PDF]
Anais Brasileiros de Dermatologia, 2019 : Background: Serum amyloid A is an acute-phase protein. There is no available data regarding serum amyloid A levels in patients with acute (AU) and chronic urticaria (CU). Objective: To investigate the association between serum amyloid A and urticaria.
Wei Lu +4 more
doaj +2 more sources
Diagnosis of neonatal and adult sepsis using a Serum Amyloid A lateral flow test. [PDF]
PLoS OneNowak J +11 more
europepmc +2 more sources