Serum amyloid A4 is a procoagulant apolipoprotein that it is elevated in venous thrombosis patients
Background Serum amyloid A4 (SAA4) is an apolipoprotein that is in the SAA family and it is constitutively translated. Previously, acute‐phase SAA1 and SAA2 levels were associated with venous thromboembolism (VTE).
José A. Fernández +3 more
doaj +1 more source
The effects of peripheral and central high insulin on brain insulin signaling and amyloid-β in young and old APP/PS1 mice [PDF]
Hyperinsulinemia is a risk factor for late-onset Alzheimer's disease (AD). In vitro experiments describe potential connections between insulin, insulin signaling, and amyloid-β (Aβ), but in vivo experiments are needed to validate these relationships ...
Caesar, Emily E +9 more
core +2 more sources
Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice [PDF]
Insulin resistance and impaired glucose homoeostasis are important indicators of Type 2 diabetes and are early risk factors of AD (Alzheimer's disease).
Alex J. Harper +62 more
core +4 more sources
Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. [PDF]
The cause(s) of sporadic Alzheimer's disease (sAD) are complex and currently poorly understood. They likely result from a combination of genetic, environmental, proteomic and lipidomic factors that crucially occur only in the aged brain.
Green, Kim N
core +1 more source
Evaluating Serum Amyloid A as a Biomarker in Preeclampsia [PDF]
Background: Preeclampsia (PE) is the major cause of perinatal morbidity and mortality. The causes of the condition can be ascribed to excessive maternal systemic inflammatory response to pregnancy. Emerging evidence indicates that serum amyloid A (SAA),
Montadhar K. Sultan +2 more
doaj +1 more source
Salivary and serum levels of serum amyloid a, haptoglobin, ceruloplasmin and albumin in neonatal calves with diarrhoea [PDF]
This study was aimed at the determination of the serum levels of serum amyloid A (SAA), haptoglobin (Hp), ceruloplasmin (Cp) and albumin (Alb), and the salivary levels of Hp and Cp in neonatal calves with diarrhoea.
Ekin Emre ERKILIÇ +5 more
doaj +1 more source
The goal of this study was to analyze the genetic expression of antiretroviral restriction factors (ARF) and acute phase proteins (APP), as well as their correlation with proviral and viral loads in cattle with aleukemic (AL) and persistent lymphocytosis
Ana S. González-Méndez +3 more
doaj +1 more source
Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly. [PDF]
In cognitively normal (CN) elderly individuals, white matter hyperintensities (WMH) are commonly viewed as a marker of cerebral small vessel disease (SVD).
Alzheimer’s Disease Neuroimaging Initiative +7 more
core +2 more sources
Serum amyloid A1 (SAA1) protein in human colostrum
Proteins of the serum amyloid A (SAA) family have been remarkably conserved in evolution. Their biologic function(s) are not fully defined but they are likely to be a part of primordial host defense.
George H. Sack Jr +6 more
doaj +1 more source
Relationship between haptoglobin and serum amyloid A in milk and milk quality [PDF]
The objective of this study was to evaluate relationships between the presence in milk of the major bovine acute phase proteins, haptoglobin (Hp) and serum amyloid A (SAA), and milk quality parameters.
Bach Larsen, Lotte +4 more
core +1 more source

