Results 251 to 260 of about 275,854 (308)
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Serum amyloid a production in chicken embryonic synovial fibroblasts induced by lipopolysaccharide, interleukin-1β, and vitamin A. [PDF]
Dayı B +4 more
europepmc +1 more source
ABSTRACT Purpose Ferritin's iron core exhibits complex magnetic properties, as suggested by magnetometry and Mössbauer spectroscopy, which remain incompletely understood. In particular, the antiferromagnetic inner core could influence the accuracy of iron quantification using MRI and raise concerns about postmortem validation studies involving degraded
Stefan Ropele +8 more
wiley +1 more source
Serum amyloid A and proadrenomedullin as early markers in critically ill children with sepsis. [PDF]
Saleh NY +3 more
europepmc +1 more source
Liver Steatosis in Induced Hepatocytes From Carriers of Spinal Muscular Atrophy
ABSTRACT Introduction/Aims Although classically characterized as a motor neuron disease, spinal muscular atrophy (SMA) is increasingly recognized as a multisystem disorder. We previously showed hepatocyte‐intrinsic steatosis in SMA, raising the question of whether SMA carriers, who are typically asymptomatic, may also exhibit subclinical hepatic ...
Lingyu Sun +15 more
wiley +1 more source
Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov +3 more
wiley +1 more source
Evaluation of myeloid-related protein 126, cardiac troponin C and serum amyloid A as potential plasma biomarkers of health and disease in sea turtles. [PDF]
Marancik DP +6 more
europepmc +1 more source
Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto +2 more
wiley +1 more source

