Results 261 to 270 of about 275,854 (308)

Functional Interactions Between Recombinant Serum Amyloid A1 (SAA1) and Chemokines in Leukocyte Recruitment. [PDF]

Int J Mol Sci
Van Damme J, Struyf S, Proost P, Opdenakker G, Gouwy M.   +4 more
europepmc   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Erratum for "Prognostic Potential of Copper, Zinc, Copper/Zinc Ratio, Cobalamin, and Serum Amyloid A in Cats With Panleukopenia". [PDF]

J Vet Intern Med
europepmc   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Balancing inflammation: the specific roles of serum amyloid A proteins in sterile and infectious diseases. [PDF]

Front Immunol
Mohanty T, Miličević K, Göthert H, Tillmann A, Padra M, Papareddy P, Herwald H.   +6 more
europepmc   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

Small Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto, Nine R. Kok, Philipp C. Hauger, Manon Karsten‐van Diepen, Michael de Kok, Nanne J. Paauw, Susanne M. A. van der Pol, Joline P. Nugteren‐Boogaard, Peter L. Hordijk, Stephanie D. Beekhuis‐Hoekstra, Susan Gibbs, Nienke M. de Wit, Helga E. de Vries   +12 more
wiley   +1 more source

Elucidating the Mechanism of Recognition and Binding of Heparin to Amyloid Fibrils of Serum Amyloid A. [PDF]

Biochemistry
Abraham CB, Lewkowicz E, Gursky O, Straub JE.   +3 more
europepmc   +1 more source

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

Veterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin, Ariadne Rein, Isabella de Almeida Fabris, Beatriz Gasser, Luiz Paulo Nogueira Aires, Bruna Bressianini Lima, Daniele Azevedo Gandra, Daniela Gomes da Silva, Ricardo Andrés Ramirez Uscategui, Gabriela Castro Lopes Evangelista, Marcus Antônio Rossi Feliciano, Paola Castro Moraes   +11 more
wiley   +1 more source

Serum Concentrations of Imidazole Dipeptides and Serum Amyloid A in a Bottlenose Dolphin (<i>Tursiops truncatus</i>) with Rhabdomyolysis: Potential Biomarkers for Muscular Damage. [PDF]

Animals (Basel)
Arakawa N, Otsuka M, Hamano T, Kumagai M, Kato S, Hirai T, Yabuki A, Yamato O.   +7 more
europepmc   +1 more source

Modulation of islet amyloid polypeptide induced β-cell toxicity and amyloid formation by serum albumin proteins

Alexander Zhyvoloup, Zachary Ridgway, A Prashanth, Daniel P. Raleigh   +3 more
openalex   +2 more sources