Advanced Science, EarlyView.Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang +13 more
wiley +1 more source
BiomedicinesBackground: Acute pancreatitis is an inflammation of the pancreas with variable outcomes depending on its severity. Multiple systems of prediction have been proposed, each with variable specificity and sensitivity and with uneven clinical use.
Mihaela Cristina Pavalean +9 more
doaj +1 more source
Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact
Advanced Science, EarlyView.Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou +16 more
wiley +1 more source
Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis [PDF]
, 2018 Osteoporosis is associated with chronic iron overload secondary to hereditary hemochromatosis (HH), but the causative mechanisms are incompletely understood.
Camacho, António +7 more
core +4 more sources
Evaluation of the Relationship between Serum Ferritin Level and Renal Function in Patients with Thalassemia Major [PDF]
, 2021 Alireza Eskandarifar, yasin padash
openalex +1 more source
New approaches to treating chronic obstructive pulmonary disease with Colla corii asini
Animal Models and Experimental Medicine, EarlyView.Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang +5 more
wiley +1 more source
Evaluation of Serum Ferritin Levels in Patients of Hypothyroidism [PDF]
Indian Journal of Medical BiochemistryBackground: The thyroid gland is a bilobed endocrine gland that secretes two vital hormones: thyroxine (T4) and triiodothyronine (T3). The production and release of these hormones are regulated by the thyroid-stimulating hormone (TSH) from the pituitary ...
Vartika Saini +3 more
doaj +1 more source
CSF and serum ferritin levels in narcolepsy type 1 comorbid with restless legs syndrome
Annals of Clinical and Translational Neurology, 2020 Objectives To investigate whether cerebrospinal fluid (CSF) and serum ferritin levels differ between patients with narcolepsy type 1 (NT1) comorbid with restless legs syndrome (RLS) or periodic leg movements during sleep (PLMS), and patients with NT1 or ...
Lucie Barateau +8 more
doaj +1 more source
The effect of a meat extract on iron absorption in young women : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Human Nutrition at Massey University, Palmerston North Campus, New Zealand [PDF]
, 2007 Iron deficiency is a global problem for which determinants and solutions need to be investigated. The first part of this study assessed the iron status and dietary intakes of 85 non vegetarian women aged 18-40 years living in the Manawatu region ...
Beck, Kathryn Louise
core
Urinary porphyrin excretion in hepatitis C infection [PDF]
, 1999 A high prevalence of hepatitis C virus infection in porphyria cutanea tarda in some populations suggests a close link between viral hepatitis and alteration of porphyrin metabolism.
Jacob, Karl +2 more
core +1 more source