Results 51 to 60 of about 1,950,451 (304)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Ischaemic strokes in patients with pulmonary arteriovenous malformations and hereditary hemorrhagic telangiectasia: associations with iron deficiency and platelets. [PDF]

, 2014
25/03/14 meb. OA paper , Ok to add.Background: Pulmonary first pass filtration of particles marginally exceeding ~7 µm (the size of a red blood cell) is used routinely in diagnostics, and allows cellular aggregates forming or entering the circulation in ...
John A Livesey, Michael A. Laffan (367175), Tighe Hannah C., Richard Manning (524799), James E Jackson, James E. Jackson (524802), Gillian Angus, Tighe, HC, Meek John, Jackson James E., Gillian Angus (367169), Claire L Shovlin, Livesey, J, Basel Chamali (524796), John A. Livesey (524798), Hannah C. Tighe (524801), Laffan, MA, Basel Chamali, Vatshalan Santhirapala (524797), Jackson, JE, Meek, J, Chamali Basel, Manning Richard, Chamali, B, Michael A Laffan, Hannah C Tighe, Claire L. Shovlin (367168), Manning, R, Livesey John A., Shovlin, CL, Angus Gillian, Santhirapala, V, Santhirapala Vatshalan, John Meek, Shovlin Claire L., Vatshalan Santhirapala, Richard Manning, Laffan Michael A., John Meek (524800)   +38 more
core   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Dietary iron intervention using a staple food product for improvement of iron status in female runners. [PDF]

, 2014
This article has been made available through the Brunel Open Access Publishing Fund.Adequate nutrient intake is critically important for achieving optimal sports performance.
Derbyshire, E, Ieva Alaunyte, Valentina Stojceska, Alaunyte, I, Stojceska, V, Plunkett, A, Andrew Plunkett, Emma Derbyshire   +7 more
core   +1 more source

Biomimetic Core–Shell Liposome Nanoparticles Deplete Lipoproteins and Enhance the Purity of Extracellular Vesicles from Human Blood

Advanced Functional Materials, EarlyView.
Lipoprotein‐mimicking nanoparticles (SL‐NPs), comprising Fe3O4@SiO2 cores coated with liposomal bilayers, selectively capture lipoproteins through protein corona formation. The resulting SL‐NP‐lipoprotein complexes can be removed by low‐speed centrifugation, thereby enhancing the purity of small extracellular vesicles (sEVs) isolated from human serum ...
Man‐Di Wang, Andrew J. Perciaccante, David Inman, Bong Hwan Sung, Alissa M. Weaver, Suzanne M. Ponik, Ying Ge, Song Jin   +7 more
wiley   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

VividLife Serum Reviews

, 2021
Would you be able to Expect The Results To Stay? This relies upon how long you would apply VividLife Serum cream to your skin. In the event that you have utilized the VividLife Serum cream for a constant 3 months or more than that, then, at that point ...
VividLife Serum
core   +1 more source

Unique Role of Microstructure of a Bioimplant Zinc Alloy and Protein Content of Simulated Body Fluid in Corrosion and Fracture

Advanced Functional Materials, EarlyView.
BSA addition to physiological solutions enhances resistance of a Zn alloy to stress corrosion cracking (SCC) but reduces its corrosion resistance. Extended surface characterization explains the contrasting influences on corrosion and SCC. Unexpectedly, the alloy suffers transgranular SCC (TGSCC), despite extensive grain boundary precipitation. Thorough
RK Singh Raman, Syed Hussain Wajahat, Saad Al‐Saadi, Robin E. Schäublin, Peng Zeng, Solomon Ansah, Jixing Lin, Xian Tong, Cuie Wen, Jörg F. Löffler   +9 more
wiley   +1 more source

Correlation of serum iron and chronic kidney diseasestages: A cross-sectional study

Journal of Health Sciences
Introduction: Chronic kidney disease (CKD) is a progressive disorder characterized by a gradual loss of renal function and frequent disturbances in iron metabolism. These disturbances often lead to iron deficiency and anemia. Serum iron and ferritin are
Mervana Marić, Dalila Smajlović, Emina Hodžić, Arzija Pašalić, Samra Hadžiahmić Limo, Lejla Čano Dedić   +5 more
doaj   +1 more source