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Neutral endopeptidase activity in serum and cerebrospinal fluid. [PDF]

open access: possibleHiroshima journal of medical sciences, 1997
We measured neutral endopeptidase (NEP) activity in serum from non-smoking healthy Japanese and in cerebrospinal fluid (CSF) from patients without neurological or inflammatory diseases. The serum NEP activity (sNEP) of 25 males and 25 females, aged 20 to 65 years, ranged from 0.003 to 1.62 pmole/min/microliter.
Muraki, Koutarou   +5 more
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Neutral α-mannosidase activity in human serum

Biochimica et Biophysica Acta (BBA) - Enzymology, 1976
Two types of alpha-mannosidase (alpha-D-mannoside mannohydrolase, EC 3.2.1.24) with neutral pH optima exist in serum. The activity with an optimum between pH 6.0 and 6.4 is similar to alpha-mannosidase C, described earlier in tissues. The second activity, with a pH optimum between pH 5.2 and 5.8 is the dominant form in serum.
B, Hultberg, P K, Masson, S, Sjöblad
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Neutral glycosphingolipids of serum lipoproteins in Fabry's disease

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1976
The neutral glycosphingolipid compositions of lipoprotein fractions of serum from eight healthy male volunteers and three patients with Fabry's disease were determined. Four fractions were studied: very low density lipoprotein (VLDL, d less than 1.006); low density lipoprotein (LDL, d 1.006-1.063); high density lipoprotein (HDL, d 1.063-1.21); and ...
J T, Clarke, J M, Stoltz, M R, Mulcahey
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Serum Enterotoxin-neutralizing Antibody in Human Shigellosis

Nature New Biology, 1973
THE neurotoxin of Shiga's bacillus (Shigella dysenteriae 1), known for 70 years1 and nearly as potent as botulinus toxin2, has not been considered to play a role in human shigellosis3, partly because no strain of shigella other than Shiga's has been found to produce the exotoxin2.
G T, Keusch, M, Jacewicz
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Neutralization of Silkworm Jaundice Virus by Human Serum

Nature, 1954
IT is well known that immunized rabbit serum neutralizes the virus of silkworm jaundice, but there seems to be no information on the effect of human serum. Human sera were obtained from people working on silkworm jaundice virus and from others. Supernatant fluid from the infected larval blood was used as the virus solution.
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Neutralization of saxitoxin by anti-saxitoxin rabbit serum

Toxicon, 1985
This study examined the ability of anti-saxitoxin rabbit serum to neutralize saxitoxin, both in vitro and in vivo. In vitro, two rabbit antisera decreased [3H]-saxitoxin binding to specific sites in rat brain membranes. The more potent of these sera, antiserum A, when combined with saxitoxin in vitro, decreased saxitoxin's lethal potency based on mouse
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Neutralization of Vaccine Virus by Immune Serum

The Journal of Immunology, 1941
Summary and Discussion Experiments have been performed with a view to gaining information on the protection afforded by immune serum against vaccinal infection of mice, and in order to correlate the protective potency of serum against virus introduced intracerebrally in mice with that introduced intracutaneously in rabbits.
L H Bronson, R F Parker
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Studies on the Bacteriophage Neutralizing Activity of Serums

The Journal of Immunology, 1962
Summary Immunization of rabbits with T2 phage results in the early development of neutralizing Ab which, except for its elevated titer, is indistinguishable from the Ab present prior to immunization and designated as normal Ab. Subsequently, Ab is formed which occurs in an additional Cohn fraction and, in contrast to the C′ dependence of
Andre J Toussaint, Louis H Muschel
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The Neutralization of Western Equine Encephalomyelitis Virus by Human Convalescent Serum. The Influence of Heat Labile Substances in Serum on the Neutralization Index

The Journal of Immunology, 1947
Summary Evidence is presented to show that a heat labile accessory substance which augments the activity of neutralizing antibodies to Western equine encephalomyelitis virus is present in normal serum. This substance loses most of its activity when diluted 1:10.
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Antigenic analysis of polioviruses by kinetic studies of serum neutralization

Virology, 1959
Abstract Kinetic studies of the serum neutralization of polioviruses show that each strain can be uniquely specified by its homologous antiserum. Heterologous strains are neutralized more slowly than is the homologous strain. Late antisera are somewhat less specific than early antisera. The antigenic character is highly stable for this virus. Strains
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