Results 111 to 120 of about 151,984 (257)

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Association of serum prostate-specific antigen (PSA) level and circulating tumor cell-based PSA mRNA in prostate cancer. [PDF]

Prostate Int, 2022
Cho H, Oh CK, Cha J, Chung JI, Byun SS, Hong SK, Chung JS, Han KH.   +7 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Influence of Tumor Burden on Serum Prostate-Specific Antigen in Prostate Cancer Patients Undergoing Radical Prostatectomy. [PDF]

Front Oncol, 2021
Mandel P, Hoeh B, Preisser F, Wenzel M, Humke C, Welte MN, Jerrentrup I, Köllermann J, Wild P, Tilki D, Haese A, Becker A, Roos FC, Chun FKH, Kluth LA.   +14 more
europepmc   +1 more source

Autonomic Plexuses of the Female Sexual Organs Travel Within Pubocervical and Rectovaginal [Endopelvic] Fascia: A Rationale for ‘Nerve‐Aware’ Vaginal Prolapse Repair

Clinical Anatomy, EarlyView.
ABSTRACT The connective tissue support of female pelvic viscera—endopelvic fascia—has been studied in fetal and immunohistochemical models to demonstrate its relationship with the autonomic nerves of the female pelvis. Due to a paucity of literature examining the gross anatomical relationships between endopelvic fascia and autonomic nerves in adult ...
Stephen Magliocchetti, Benjamin Laxer, Leyla Spennato, Norah Alturki, Queena Chou, Tyler S. Beveridge   +5 more
wiley   +1 more source

Association of True Positivity with Serum Prostate-Specific Antigen Levels and Other Clinical Factors in Indeterminate PSMA-RADS-3A Lesions Identified on ¹⁸F-DCFPyL PET/CT Scans. [PDF]

Tomography, 2022
Garg T, Werner RA, Chung HW, Khatri W, Pienta KJ, Pomper MG, Gorin MA, Saad E, Rowe SP.   +8 more
europepmc   +1 more source

Extracellularly Activatable Conjugates of RGD Peptidomimetics and Cryptophycin for αVβ3‐Targeted Cancer Therapy

Chemistry – A European Journal, EarlyView.
Integrin αVβ3‐targeting small‐molecule drug conjugates (SMDCs) were synthesized by conjugating a cryptophycin payload through a neutrophil elastase‐cleavable NPV‐PABC linker. RGD peptidomimetic and linker epimers served as controls for targeting and enzymatic cleavage, and the resulting conjugates displayed subnanomolar cytotoxicity in vitro.
Dominic Seißenschmidt, Henriette Hartung, Jonah Kammer, Norbert Sewald   +3 more
wiley   +1 more source

Design, Synthesis and Evaluation of a Prostate-Specific Antigen Rapid Test Strip [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Background and Objective: Early detection of all cancers, including prostate cancer, is considerably helpful in their treatment. In addition to clinical examination of the prostate gland, prostate-specific antigen (PSA) is also used to diagnose prostate ...
M Shahri, E Ferdosi-Shahandashti, GA Kardar   +2 more
doaj  

Clinical Effects of Jiawei Danggui Beimu Kushen Pills in the Treatment of Prostate Cancer and Their Influence on the Expression of Serum Prostate Specific Antigen. [PDF]

Evid Based Complement Alternat Med, 2021
Zhao H, Ren Z, Wang G.
europepmc   +1 more source

Loss of Twist1 leads to disruption of ciliary length, endocytic vesicle dynamics, and cell–cell junctions during neural tube formation

Developmental Dynamics, EarlyView.
Abstract Background Endocytosis constitutes a fundamental cellular process governing development through coordinated regulation of plasma membrane remodeling and ciliogenesis, processes essential for cell shape changes and tissue development. Although Twist1 null embryos display complete cranial neural tube (NT) closure defects and conditional knockout
Derrick Thomas, Brittany M. Hufft‐Martinez, Zarna Lalwani, Vi Pham, Mary Elmeniawi, An J. Tran, Jianming Xu, Irfan Saadi, Walid D. Fakhouri   +8 more
wiley   +1 more source