Results 1 to 10 of about 120,528 (253)
Tumor Biology, 1999 Approximately 40% of the prostate-specific antigen (PSA) purified from seminal fluid comprises cleaved or fragmented forms of PSA. These fragments are observed by reduced SDS-PAGE and have been identified in preparations of purified seminal plasma. The comparative analysis of 53 antibodies, submitted to an international PSA Workshop, with different PSA
T J, Wang +5 more
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Asian Journal of Andrology, 2015 In Western countries, clinical trials on prostate cancer screening demonstrated a limited benefit for patient survival. In the Asia-Pacific region, including Japan, the rate of prostate-specific antigen (PSA) testing remains very low compared with ...
Yasuhide Kitagawa, Mikio Namiki
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Biology of prostate-specific antigen
Urology, 2003 The human kallikrein (hk) family, located on chromosome 19, encodes prostate-specific antigen (PSA [or hK3]), hK2, hK4, and hK15 (prostin), as well as other serine proteases. Although PSA has been used in the detection of prostate cancer for several years, much remains unknown about its function and forms.
Steven P, Balk +2 more
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Clinical and Translational Radiation Oncology, 2022 Background and purpose: The treatment of biochemical recurrence (BCR) after prostatectomy is challenging as the site of the recurrence is often undetectable.
Adalsteinn Gunnlaugsson +10 more
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Prostate Specific Antigen: A review [PDF]
Acta Oncologica, 1991 Despite its identification in the 1970s, prostate specific antigen (PSA) has only recently gained widespread utility. In this review, we will describe significant aspects of the biochemistry of PSA, immunohistochemical applications, the effect of prostatic manipulation on the serum level of this analyte, and other considerations in the determination of
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Prostate-Specific Antigen in Ascitic Fluid [PDF]
Clinical Chemistry, 1997 Although previously thought to be produced almost exclusively by the epithelial cells of the prostate (1), prostate-specific antigen (PSA) is produced and secreted by several extraprostatic sources (2)(3). Considering the high degree of homology of PSA with the human glandular kallikrein (hKGK1) (4)(5) and the activation of the kallikrein–kinin system ...
MANNELLO, FERDINANDO +3 more
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The diagnostic value of a new formula combining age and prostate volume in prostate cancer
Journal of Men's Health, 2022 Background and objective: This study combined two clinical indicators (age and prostate volume (PV)) to generate age to PV (AVR) ratio, whose diagnostic value for prostate cancer (PCa) was examined based on prostate specific antigen (PSA) in the range
Xiaobo Yang +8 more
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Review on the simultaneous determination of total prostate-specific antigen and free prostate-specific antigen [PDF]
The Prostate, 1996 The total prostate-specific antigen (t-PSA) in serum measured by PSA assays represents the sum of free (f-PSA) and PSA complexed with alpha 1-antichymotrypsin. The f-PSA/t-PSA (F/T) ratio in prostate cancer (PCA) patients is lower than in patients suffering from benign prostatic hyperplasia (BPH).
Iersel, M.P. van +5 more
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Journal of Experimental & Clinical Cancer Research, 2010 Background The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role ...
Nouira Yassin +8 more
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The effects of specific expression of apoptin under the control of PSES and PSA promoter on cell death and apoptosis of LNCaP cells [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): Apoptotic effect of apoptin has been demonstrated in numerous studies. However, its tumor specificity has been questioned by some reports.
Vida Mohammadi +6 more
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