Results 21 to 30 of about 6,497 (208)
Glycotyping of prostate specific antigen [PDF]
Measurement of serum levels of the prostate specific antigen (PSA) is now widely used for the diagnosis of prostate cancer and benign prostate hyperplasia. This serum marker is of value since it is derived only from the tissue of interest, but increased levels of PSA in serum do not allow a completely clear cut diagnosis of benign versus malignant ...
S, Prakash, P W, Robbins
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Approximately 40% of the prostate-specific antigen (PSA) purified from seminal fluid comprises cleaved or fragmented forms of PSA. These fragments are observed by reduced SDS-PAGE and have been identified in preparations of purified seminal plasma. The comparative analysis of 53 antibodies, submitted to an international PSA Workshop, with different PSA
T J, Wang +5 more
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In Western countries, clinical trials on prostate cancer screening demonstrated a limited benefit for patient survival. In the Asia-Pacific region, including Japan, the rate of prostate-specific antigen (PSA) testing remains very low compared with ...
Yasuhide Kitagawa, Mikio Namiki
doaj +1 more source
Prostate-Specific Antigen in Ascitic Fluid [PDF]
Although previously thought to be produced almost exclusively by the epithelial cells of the prostate (1), prostate-specific antigen (PSA) is produced and secreted by several extraprostatic sources (2)(3). Considering the high degree of homology of PSA with the human glandular kallikrein (hKGK1) (4)(5) and the activation of the kallikrein–kinin system ...
MANNELLO, FERDINANDO +3 more
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Background and purpose: The treatment of biochemical recurrence (BCR) after prostatectomy is challenging as the site of the recurrence is often undetectable.
Adalsteinn Gunnlaugsson +10 more
doaj +1 more source
Biology of Prostate-Specific Antigen
Prostate-specific antigen (PSA) is an androgen-regulated serine protease produced by both prostate epithelial cells and prostate cancer (PCa) and is the most commonly used serum marker for cancer. It is a member of the tissue kallikrein family, some of the members of which are also prostate specific.
Steven P, Balk +2 more
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Review on the simultaneous determination of total prostate-specific antigen and free prostate-specific antigen [PDF]
The total prostate-specific antigen (t-PSA) in serum measured by PSA assays represents the sum of free (f-PSA) and PSA complexed with alpha 1-antichymotrypsin. The f-PSA/t-PSA (F/T) ratio in prostate cancer (PCA) patients is lower than in patients suffering from benign prostatic hyperplasia (BPH).
Iersel, M.P. van +5 more
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Background The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role ...
Nouira Yassin +8 more
doaj +1 more source
The effects of specific expression of apoptin under the control of PSES and PSA promoter on cell death and apoptosis of LNCaP cells [PDF]
Objective(s): Apoptotic effect of apoptin has been demonstrated in numerous studies. However, its tumor specificity has been questioned by some reports.
Vida Mohammadi +6 more
doaj +1 more source
The diagnostic value of a new formula combining age and prostate volume in prostate cancer
Background and objective: This study combined two clinical indicators (age and prostate volume (PV)) to generate age to PV (AVR) ratio, whose diagnostic value for prostate cancer (PCa) was examined based on prostate specific antigen (PSA) in the range
Xiaobo Yang +8 more
doaj +1 more source

