Results 21 to 30 of about 233,415 (250)

Relationship between serum prostate-specific antigen and age in cadavers

SAGE Open Medicine, 2020
Objectives: An increase in number of unidentified cadavers is a growing problem. To identify these cadavers, a simple objective method is required to estimate cadaveric age.
Hajime Tsuboi, Daisuke Miyamori, Noboru Ishikawa, Hiroaki Ichioka, Hiroshi Ikegaya   +4 more
doaj   +1 more source

Investigation of prostate specific antigen glycosylation [PDF]

Journal of the Serbian Chemical Society, 2000
In the present work, prostate specific antigen (PSA) glycosylation was examined by lectin affinity methods. The results obtained indicated that PSA purified from human seminal plasma contained at least one bianntenary N-linked oligosaccharide ...
Marinović Vesna, Čuperlović Margita
doaj   +3 more sources

Prostate-specific antigen and free prostate-specific antigen/prostate-specific antigen ratio in patients with benign prostatic hyperplasia and prostate cancer

Baghdad Journal of Biochemistry and Applied Biological Sciences, 2020
Background: Prostate cancer is one of the most common cancers in men, worldwide. Many markers are suggested for prostate cancer with different specificity and sensitivity.
Amal A. Hussein, Rayah Baban, Alaa Hussein   +2 more
doaj  

What Should Be the Prostate Specific Antigen Threshold for Prostate Biopsy?

Haseki Tıp Bülteni, 2017
Aim: There is still uncertainty today regarding the prostate specific antigen (PSA) threshold for prostate biopsy. From this point of view, we aimed to investigate the PSA threshold for prostate biopsy in this study.
Hasan Deliktaş, Hayrettin Şahin
doaj   +1 more source

Early prostate-specific antigen response post-abiraterone as predictor of overall survival in metastatic castrate-resistant prostate cancer

BMC Cancer, 2019
Background Abiraterone is an important agent in the treatment of advanced prostate cancer. Early changes in prostate-specific antigen while on abiraterone in patients with metastatic castrate-resistant prostate cancer potentially have financial and ...
Joshua P. Schiff, Patrick Cotogno, Allison Feibus, Peter Steinwald, Elisa Ledet, Brian Lewis, Oliver Sartor   +6 more
doaj   +1 more source

Clinical Implications of Nadir Serum Prostate-Specific Antigen Levels After Transurethral Enucleation of the Prostate

Frontiers in Oncology, 2022
ObjectiveProstate-specific antigen levels after transurethral enucleation of the prostate may serve as indicators of residual cancer foci. The objective of this study was to investigate the association between the post-transurethral enucleation of the ...
Yung-Ting Cheng, Yung-Ting Cheng, Jian-Hua Hong, Yu-Chuan Lu, Yi-Kai Chang, Shih-Chun Hung, Kuo-Kang Feng, Shih-Ping Liu, Po-Ming Chow, Hong-Chiang Chang, Chung-Hsin Chen, Yeong-Shiau Pu   +11 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The Value of Prostate-Specific Antigen-Related Indexes and Imaging Screening in the Diagnosis of Prostate Cancer

Cancer Management and Research, 2020
Xiaojing Bai,1,2,* Yumei Jiang,1,2,* Xinwei Zhang,1,2 Meiyu Wang,3 Juanhua Tian,1 Lijun Mu,1 Yuefeng Du1,2 1Department of Urology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, People’s Republic of ...
Bai X, Jiang Y, Zhang X, Wang M, Tian J, Mu L, Du Y   +6 more
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Digital rectal examination (DRE) does not influence total serum levels of prostate specific antigen (tPSA), in individuals without prostate pathology

International Brazilian Journal of Urology, 2003
OBJECTIVE: To evaluate if the digital rectal examination (DRE) performed before determination of total serum prostate specific antigen (tPSA) influences the levels of this protein.
Maria de F. Figueirêdo, Galeno T. Lopes, Talapala G. Naidu   +2 more
doaj   +1 more source