Results 21 to 30 of about 351,379 (204)
PROSTATE-SPECIFIC ANTIGEN VELOCITY AND REPEATED MEASURES OF PROSTATE-SPECIFIC ANTIGEN
Numerous studies evaluating different populations have shown similar findings with respect to repeated PSA measurements and PSAV. First, there is substantial within-individual variability between repeated PSA measures. Second, this variability between PSA measurements precludes the use of a simple change in PSA as a marker for prostate cancer.
H B, Carter, J D, Pearson
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Supporting Information of the thesis Unravelling the Sugar-Coating of Prostate-Specific Antigen - Method Development and its Application to Prostate Cancer Research [PDF]
Supporting Information of all chapters described in the thesis Unravelling the Sugar-Coating of Prostate-Specific Antigen - Method Development and its Application to Prostate Cancer ...
Lageveen-Kammeijer, G.S.M. (Leiden University Medical Center (LUMC)), Researcher
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Approximately 40% of the prostate-specific antigen (PSA) purified from seminal fluid comprises cleaved or fragmented forms of PSA. These fragments are observed by reduced SDS-PAGE and have been identified in preparations of purified seminal plasma. The comparative analysis of 53 antibodies, submitted to an international PSA Workshop, with different PSA
T J, Wang +5 more
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Biology of prostate-specific antigen
The human kallikrein (hk) family, located on chromosome 19, encodes prostate-specific antigen (PSA [or hK3]), hK2, hK4, and hK15 (prostin), as well as other serine proteases. Although PSA has been used in the detection of prostate cancer for several years, much remains unknown about its function and forms.
Steven P, Balk +2 more
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Prostate Specific Antigen: A review [PDF]
Despite its identification in the 1970s, prostate specific antigen (PSA) has only recently gained widespread utility. In this review, we will describe significant aspects of the biochemistry of PSA, immunohistochemical applications, the effect of prostatic manipulation on the serum level of this analyte, and other considerations in the determination of
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Prostate-Specific Antigen in Ascitic Fluid [PDF]
Although previously thought to be produced almost exclusively by the epithelial cells of the prostate (1), prostate-specific antigen (PSA) is produced and secreted by several extraprostatic sources (2)(3). Considering the high degree of homology of PSA with the human glandular kallikrein (hKGK1) (4)(5) and the activation of the kallikrein–kinin system ...
MANNELLO, FERDINANDO +3 more
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In Western countries, clinical trials on prostate cancer screening demonstrated a limited benefit for patient survival. In the Asia-Pacific region, including Japan, the rate of prostate-specific antigen (PSA) testing remains very low compared with ...
Yasuhide Kitagawa, Mikio Namiki
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Review on the simultaneous determination of total prostate-specific antigen and free prostate-specific antigen [PDF]
The total prostate-specific antigen (t-PSA) in serum measured by PSA assays represents the sum of free (f-PSA) and PSA complexed with alpha 1-antichymotrypsin. The f-PSA/t-PSA (F/T) ratio in prostate cancer (PCA) patients is lower than in patients suffering from benign prostatic hyperplasia (BPH).
Iersel, M.P. van +5 more
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Prostate specific antigen expression does not necessarily correlate with prostate cancer cell growth [PDF]
PURPOSE: The antiproliferative effects of pharmacological agents used for androgen ablative therapy in prostate cancer, including goserelin, bicalutamide and cyproterone acetate (Fluka Chemie, Buchs, Switzerland), were tested in vitro.
Peternac, Daniel +4 more
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Background and purpose: The treatment of biochemical recurrence (BCR) after prostatectomy is challenging as the site of the recurrence is often undetectable.
Adalsteinn Gunnlaugsson +10 more
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