Results 21 to 30 of about 6,497 (208)

Glycotyping of prostate specific antigen [PDF]

open access: yesGlycobiology, 2000
Measurement of serum levels of the prostate specific antigen (PSA) is now widely used for the diagnosis of prostate cancer and benign prostate hyperplasia. This serum marker is of value since it is derived only from the tissue of interest, but increased levels of PSA in serum do not allow a completely clear cut diagnosis of benign versus malignant ...
S, Prakash, P W, Robbins
openaire   +2 more sources

Western Blotting Analysis of Antibodies to Prostate-Specific Antigen: Specificities for Prostate-Specific Antigen and Prostate-Specific Antigen Fragments

open access: yesTumor Biology, 1999
Approximately 40% of the prostate-specific antigen (PSA) purified from seminal fluid comprises cleaved or fragmented forms of PSA. These fragments are observed by reduced SDS-PAGE and have been identified in preparations of purified seminal plasma. The comparative analysis of 53 antibodies, submitted to an international PSA Workshop, with different PSA
T J, Wang   +5 more
openaire   +2 more sources

Prostate-specific antigen-based population screening for prostate cancer: current status in Japan and future perspective in Asia

open access: yesAsian Journal of Andrology, 2015
In Western countries, clinical trials on prostate cancer screening demonstrated a limited benefit for patient survival. In the Asia-Pacific region, including Japan, the rate of prostate-specific antigen (PSA) testing remains very low compared with ...
Yasuhide Kitagawa, Mikio Namiki
doaj   +1 more source

Prostate-Specific Antigen in Ascitic Fluid [PDF]

open access: yesClinical Chemistry, 1997
Although previously thought to be produced almost exclusively by the epithelial cells of the prostate (1), prostate-specific antigen (PSA) is produced and secreted by several extraprostatic sources (2)(3). Considering the high degree of homology of PSA with the human glandular kallikrein (hKGK1) (4)(5) and the activation of the kallikrein–kinin system ...
MANNELLO, FERDINANDO   +3 more
openaire   +3 more sources

A prospective phase II study of prostate-specific antigen-guided salvage radiotherapy and 68Ga-PSMA-PET for biochemical relapse after radical prostatectomy – The PROPER 1 trial

open access: yesClinical and Translational Radiation Oncology, 2022
Background and purpose: The treatment of biochemical recurrence (BCR) after prostatectomy is challenging as the site of the recurrence is often undetectable.
Adalsteinn Gunnlaugsson   +10 more
doaj   +1 more source

Biology of Prostate-Specific Antigen

open access: yesJournal of Clinical Oncology, 2003
Prostate-specific antigen (PSA) is an androgen-regulated serine protease produced by both prostate epithelial cells and prostate cancer (PCa) and is the most commonly used serum marker for cancer. It is a member of the tissue kallikrein family, some of the members of which are also prostate specific.
Steven P, Balk   +2 more
openaire   +6 more sources

Review on the simultaneous determination of total prostate-specific antigen and free prostate-specific antigen [PDF]

open access: yesThe Prostate, 1996
The total prostate-specific antigen (t-PSA) in serum measured by PSA assays represents the sum of free (f-PSA) and PSA complexed with alpha 1-antichymotrypsin. The f-PSA/t-PSA (F/T) ratio in prostate cancer (PCA) patients is lower than in patients suffering from benign prostatic hyperplasia (BPH).
Iersel, M.P. van   +5 more
openaire   +6 more sources

Co-expression and impact of prostate specific membrane antigen and prostate specific antigen in prostatic pathologies

open access: yesJournal of Experimental & Clinical Cancer Research, 2010
Background The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role ...
Nouira Yassin   +8 more
doaj   +1 more source

The effects of specific expression of apoptin under the control of PSES and PSA promoter on cell death and apoptosis of LNCaP cells [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2017
Objective(s): Apoptotic effect of apoptin has been demonstrated in numerous studies. However, its tumor specificity has been questioned by some reports.
Vida Mohammadi   +6 more
doaj   +1 more source

The diagnostic value of a new formula combining age and prostate volume in prostate cancer

open access: yesJournal of Men's Health, 2022
Background and objective: This study combined two clinical indicators (age and prostate volume (PV)) to generate age to PV (AVR) ratio, whose diagnostic value for prostate cancer (PCa) was examined based on prostate specific antigen (PSA) in the range
Xiaobo Yang   +8 more
doaj   +1 more source

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