Results 31 to 40 of about 8,268,208 (290)
Prostate-Specific Antigen in Ascitic Fluid [PDF]
Clinical Chemistry, 1997 Although previously thought to be produced almost exclusively by the epithelial cells of the prostate (1), prostate-specific antigen (PSA) is produced and secreted by several extraprostatic sources (2)(3). Considering the high degree of homology of PSA with the human glandular kallikrein (hKGK1) (4)(5) and the activation of the kallikrein–kinin system ...
MANNELLO, FERDINANDO +3 more
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Transcriptional regulation of prostate kallikrein-like genes by androgen. [PDF]
, 1992 Using gene-specific synthetic oligonucleotides the expression and regulation of kallikrein-like genes in the human prostatic cancer cell line LNCaP were studied.
Schulz, Peter +2 more
core +1 more source
Evaluation of Phage Display Discovered Peptides as Ligands for Prostate-Specific Membrane Antigen (PSMA) [PDF]
, 2013 The aim of this study was to identify potential ligands of PSMA suitable for further development as novel PSMA-targeted peptides using phage display technology. The human PSMA protein was immobilized as a target followed by incubation with a 15-mer phage
Shen, Duanwen +15 more
core +2 more sources
Biology of Prostate-Specific Antigen
Journal of Clinical Oncology, 2003 Prostate-specific antigen (PSA) is an androgen-regulated serine protease produced by both prostate epithelial cells and prostate cancer (PCa) and is the most commonly used serum marker for cancer. It is a member of the tissue kallikrein family, some of the members of which are also prostate specific.
Steven P, Balk +2 more
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Review on the simultaneous determination of total prostate-specific antigen and free prostate-specific antigen [PDF]
The Prostate, 1996 The total prostate-specific antigen (t-PSA) in serum measured by PSA assays represents the sum of free (f-PSA) and PSA complexed with alpha 1-antichymotrypsin. The f-PSA/t-PSA (F/T) ratio in prostate cancer (PCA) patients is lower than in patients suffering from benign prostatic hyperplasia (BPH).
Iersel, M.P. van +5 more
openaire +6 more sources
The effects of specific expression of apoptin under the control of PSES and PSA promoter on cell death and apoptosis of LNCaP cells [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): Apoptotic effect of apoptin has been demonstrated in numerous studies. However, its tumor specificity has been questioned by some reports.
Vida Mohammadi +6 more
doaj +1 more source
Clinical and Translational Radiation Oncology, 2022 Background and purpose: The treatment of biochemical recurrence (BCR) after prostatectomy is challenging as the site of the recurrence is often undetectable.
Adalsteinn Gunnlaugsson +10 more
doaj +1 more source
Journal of Experimental & Clinical Cancer Research, 2010 Background The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role ...
Nouira Yassin +8 more
doaj +1 more source
The diagnostic value of a new formula combining age and prostate volume in prostate cancer
Journal of Men's Health, 2022 Background and objective: This study combined two clinical indicators (age and prostate volume (PV)) to generate age to PV (AVR) ratio, whose diagnostic value for prostate cancer (PCa) was examined based on prostate specific antigen (PSA) in the range
Xiaobo Yang +8 more
doaj +1 more source
Prostate Specific Antigen: A review [PDF]
Acta Oncologica, 1991 Despite its identification in the 1970s, prostate specific antigen (PSA) has only recently gained widespread utility. In this review, we will describe significant aspects of the biochemistry of PSA, immunohistochemical applications, the effect of prostatic manipulation on the serum level of this analyte, and other considerations in the determination of
openaire +2 more sources