Background: Hepsin (HPN), a type II trans-membrane serine protease, has been reported to be one of the most up regulated genes in prostate cancer. The aim of the present study was to find out immuno-histochemistry based phenotypic expression of HPN in ...
Madhu Mati Goel +3 more
doaj +1 more source
Treatment options in benign prostate hyperplasia associated with lower urinary tract symptoms
Benign prostatic hyperplasia is a common cause of lower urinary tract symptoms. Men who are treated for benign prostatic hyperplasia potentially reduce their lifetime risk of acute urinary retention and the need for benign prostatic hyperplasia-related ...
Ali Atan, Altuğ Tuncel
doaj +1 more source
Interstitial laser therapy of benign prostatic hyperplasia [PDF]
The objective of interstitial laser coagulation (ILC) of benign prostatic enlargement is to achieve a marked volume reduction and to decrease bladder outlet obstruction and lower urinary tract symptoms with minimal morbidity.
Muschter, Rolf, Whitfield, Hugh
core +1 more source
Silodosin inhibits noradrenaline-activated transcription factors Elk1 and SRF in human prostate smooth muscle. [PDF]
The transcription factors Elk1 and serum response factor (SRF) are central regulators of cell cycle and phenotype in various cell types. Elk1 is activated by phosphorylation (serine-383), while activation of SRF requires its co-factor, myocardin ...
Andersson, Karl-Erik +10 more
core +2 more sources
TRANSURETHRAL THULIUM:YAG LASER VAPOENUCLEATION IN BENIGN PROSTATIC HYPERPLASIA TREATMENT
Objectives. The aim of the study was to analyze evidence based data from existing sources, regarding the role and the efficacy of transurethral Thulium:YAG laser vapoenucleation in benign prostatic hyperplasia treatment. Material and methods.
Alexei Pleșacov +2 more
doaj +3 more sources
Short-term pretreatment with a dual 5α-reductase inhibitor before bipolar transurethral resection of the prostate (b-turp): evaluation of prostate vascularity and decreased surgical blood loss in large prostates [PDF]
Objective: To investigate if short-term treatment with dutasteride (8 weeks) before bipolar transurethral resection of the prostate (B-TURP) can reduce intraoperative bleeding, as dutasteride a dual 5α-reductase inhibitor (5-ARI) blocks the conversion of
Amory +28 more
core +1 more source
Role of gangliosides in prostate pathology [PDF]
Molecular pathology of benign prostatic hyperplasia is multifactorial and involves endocrine, biochemical, immunological interactions. The mechanisms involved in the onset and progression of benign prostatic hyperplasia are: infections, 50 years of age ...
Ilinca Nicolae +2 more
doaj +1 more source
Prostate-Associated Gene 4 (PAGE4): Leveraging the Conformational Dynamics of a Dancing Protein Cloud as a Therapeutic Target. [PDF]
Prostate cancer (PCa) is a leading cause of mortality and morbidity globally. While genomic alterations have been identified in PCa, in contrast to some other cancers, use of such information to personalize treatment is still in its infancy.
Dorff, Tanya +6 more
core +3 more sources
This work investigated the spectrum-effect relationships between high performance liquid chromatography (HPLC) fingerprints and the anti-benign prostatic hyperplasia activities of aqueous extracts from Saxifraga stolonifera.
Xing-Dong Wu +8 more
doaj +1 more source
Coupling of alpha(1)-Adrenoceptors to ERK1/2 in the Human Prostate [PDF]
Introduction: alpha(1)-Adrenoceptors are considered critical for the regulation of prostatic smooth muscle tone. However, previous studies suggested further alpha(1)-adrenoceptor functions besides contraction.
Anglin IE +39 more
core +1 more source

